{"id":"W2057506802","doi":"10.1016/j.devcel.2009.08.009","title":"A Role for C. elegans Eph RTK Signaling in PTEN Regulation","year":2009,"lang":"en","type":"article","venue":"Developmental Cell","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Center for Research Resources; Canadian Institutes of Health Research; National Institutes of Health; National Health Research Institutes","keywords":"Biology; Erythropoietin-producing hepatocellular (Eph) receptor; PTEN; Cell biology; Signal transduction; Ephrin; Genetics; PI3K/AKT/mTOR pathway; Receptor tyrosine kinase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001569285,0.0006617801,0.0002217893,0.0005411676,0.0005428803,0.000680757,0.0003723334,0.0006706505,0.001962557],"category_scores_gemma":[0.0002579626,0.0002550305,0.000308359,0.0001132275,0.0004921319,0.0005476163,0.0007637281,0.0007277379,0.0005793499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005769609,"about_ca_system_score_gemma":0.0004911792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001497999,"about_ca_topic_score_gemma":0.0027566,"domain_scores_codex":[0.9998465,0.00001534758,0.00001470097,0.00003996077,0.0000411781,0.00004239923],"domain_scores_gemma":[0.9998285,0.00002212745,0.00004617657,0.00002192472,0.00002227593,0.00005908164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002080517,0.00001810342,0.0005620054,0.00004671889,0.000008225505,0.0004828212,0.00001708154,0.0003233694,0.9933032,0.001920323,0.0001632571,0.002946833],"study_design_scores_gemma":[0.00002945271,0.0001284408,0.01245023,0.0000261357,0.00003090547,0.0009095772,0.00005856115,0.004659787,0.976138,0.0006526974,0.004893156,0.00002292559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9713094,0.002808653,0.01153459,0.0008153173,0.000153248,0.00003564037,0.0009311563,0.0005549683,0.01185696],"genre_scores_gemma":[0.9901417,0.0007501805,0.003603479,0.00008941686,0.000009650383,0.00002170945,0.0002070842,0.00004858303,0.005128145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001962557,"threshold_uncertainty_score":0.006565332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007887145257513875,"score_gpt":0.2310138706849933,"score_spread":0.2231267254274794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}