{"id":"W2057560227","doi":"10.1097/aln.0000000000000647","title":"TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction","year":2015,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Physicians' Services Incorporated Foundation","keywords":"Hypoxic pulmonary vasoconstriction; TRPV4; Vasoconstriction; Transient receptor potential channel; Hypoxia (environmental); Pulmonary artery; Lung; Medicine; Intravital microscopy; Hypoxemia; Internal medicine; Endocrinology; Pharmacology; Cell biology; Anatomy; Receptor; Chemistry; Biology; Microcirculation; Oxygen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001589773,0.0001051342,0.0001576143,0.00007502164,0.0001084287,0.000009671015,0.0001557361,0.0001516363,0.00004227257],"category_scores_gemma":[0.0002596212,0.00008308292,0.00007344086,0.000144128,0.0001282603,0.00009146095,0.00002267667,0.00006297521,0.0002195981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000236987,"about_ca_system_score_gemma":0.00005450705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000117466,"about_ca_topic_score_gemma":3.094198e-7,"domain_scores_codex":[0.9990625,0.0001025092,0.0001616008,0.0003224107,0.00008581056,0.0002652064],"domain_scores_gemma":[0.99945,0.0002165565,0.00007213745,0.0001204877,0.00004213895,0.00009870919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005387221,0.0005363857,0.005107161,0.0000508126,0.0000167999,0.0002012199,0.002158984,0.0001292121,0.7661312,0.009515857,0.1237893,0.09182434],"study_design_scores_gemma":[0.0008388357,0.001127533,0.0007118908,0.000009928645,0.00001812571,0.0007098762,0.0003607179,0.00188394,0.6239014,0.01589954,0.3541847,0.0003535819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955289,0.0001154433,0.0001539715,0.001062315,0.001069334,0.000312233,0.000006214669,0.0001056853,0.001645865],"genre_scores_gemma":[0.9954277,0.00006553511,0.0001363033,0.002416738,0.0002916834,0.0000610672,0.000004799374,0.00001551171,0.001580678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2303954,"threshold_uncertainty_score":0.3388023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1105324969189032,"score_gpt":0.2985672631733496,"score_spread":0.1880347662544464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}