{"id":"W2057560227","doi":"10.1097/aln.0000000000000647","title":"TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction","year":2015,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Physicians' Services Incorporated Foundation","keywords":"Hypoxic pulmonary vasoconstriction; TRPV4; Vasoconstriction; Transient receptor potential channel; Hypoxia (environmental); Pulmonary artery; Lung; Medicine; Intravital microscopy; Hypoxemia; Internal medicine; Endocrinology; Pharmacology; Cell biology; Anatomy; Receptor; Chemistry; Biology; Microcirculation; Oxygen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002171896,0.0003350558,0.0003817544,0.0003228908,0.0002259849,0.0004478176,0.0004648733,0.0006826167,0.00388777],"category_scores_gemma":[0.0004041735,0.0002954564,0.0005738258,0.0001393057,0.0004739618,0.0003399409,0.000399247,0.000898771,0.0008897557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003419443,"about_ca_system_score_gemma":0.0002555867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004556374,"about_ca_topic_score_gemma":0.0003178344,"domain_scores_codex":[0.9996293,0.00005030354,0.00003132916,0.00008962702,0.00009282163,0.0001066093],"domain_scores_gemma":[0.9995265,0.00004978629,0.0001901723,0.00004985595,0.00005496333,0.0001287863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001807028,0.00001624441,0.0002410451,0.00003833159,0.000007303778,0.00007985037,0.000006916317,0.00004686918,0.9988116,0.0001154643,0.00007645543,0.0003791583],"study_design_scores_gemma":[0.00009021306,0.000462906,0.03370408,0.00003973202,0.00008802316,0.001613709,0.0001492409,0.003315762,0.9549232,0.0005291291,0.00506159,0.00002245242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847813,0.001897253,0.009520076,0.0004428133,0.0001552341,0.00003227906,0.0008112161,0.0003183093,0.002041636],"genre_scores_gemma":[0.9942824,0.0004394633,0.001371549,0.0001610836,0.00003030342,0.00004470312,0.0007089731,0.00004610719,0.002915439],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00388777,"threshold_uncertainty_score":0.01300591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1105324969189032,"score_gpt":0.2985672631733496,"score_spread":0.1880347662544464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}