{"id":"W2057582738","doi":"10.1210/en.2013-1363","title":"Loss of Vascular Endothelial Growth Factor A (VEGFA) Isoforms in the Testes of Male Mice Causes Subfertility, Reduces Sperm Numbers, and Alters Expression of Genes That Regulate Undifferentiated Spermatogonia","year":2013,"lang":"en","type":"article","venue":"Endocrinology","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Institutes of Health","keywords":"Endocrinology; Internal medicine; Gene isoform; Sperm; Vascular endothelial growth factor A; Biology; Vascular endothelial growth factor; Gene; Andrology; Gene expression; VEGF receptors; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001839147,0.0004684026,0.0003834646,0.0007124599,0.0002023443,0.0004443135,0.0002286315,0.0003146095,0.003385144],"category_scores_gemma":[0.0001311842,0.0003064925,0.0002936543,0.0002210304,0.0003278552,0.0002529699,0.0002592341,0.0009788466,0.0005934683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002762103,"about_ca_system_score_gemma":0.0001975733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005802783,"about_ca_topic_score_gemma":0.001284714,"domain_scores_codex":[0.9996619,0.00003401038,0.00003406583,0.00008995313,0.0001222327,0.00005775846],"domain_scores_gemma":[0.9994886,0.00002560544,0.0002203763,0.00002095725,0.00002574248,0.0002186215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001079621,0.00003515209,0.0007565682,0.00002517517,0.000009303227,0.0000371735,0.00001323681,0.00001366907,0.9979143,0.00003298636,0.00003732504,0.001017171],"study_design_scores_gemma":[0.0000511307,0.001321938,0.06057682,0.0000170335,0.00007216212,0.001497722,0.00008907061,0.000468879,0.9334219,0.00005319115,0.002416993,0.00001308729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954705,0.00152136,0.001294922,0.000118799,0.00004963394,0.00001604071,0.0005664233,0.0001589729,0.0008033425],"genre_scores_gemma":[0.987801,0.001161548,0.002474616,0.0001127779,0.00003126647,0.00004256094,0.0008673171,0.00006923122,0.007439751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003385144,"threshold_uncertainty_score":0.01132447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01978894578209787,"score_gpt":0.2467992719486863,"score_spread":0.2270103261665884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}