{"id":"W2057613402","doi":"10.1371/journal.pgen.0020027","title":"An Evaluation of the Performance of Tag SNPs Derived from HapMap in a Caucasian Population","year":2006,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University and Génome Québec Innovation Centre","funders":"Canadian Institutes of Health Research; Tartu Ülikool; Genome Canada; Burroughs Wellcome Fund","keywords":"International HapMap Project; Single-nucleotide polymorphism; Minor allele frequency; Biology; Genetics; Haplotype; Population; Allele frequency; SNP; Ancestry-informative marker; Selection (genetic algorithm); Genotype; Demography; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02338872,0.0007649164,0.0005170041,0.0008995591,0.0006187618,0.0007623734,0.0004223754,0.0008840818,0.0004658954],"category_scores_gemma":[0.02945486,0.0002373147,0.000689744,0.0007811435,0.0006232861,0.0005054091,0.0005475758,0.0002885014,0.0003935472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002740742,"about_ca_system_score_gemma":0.0003581702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003670981,"about_ca_topic_score_gemma":0.002983303,"domain_scores_codex":[0.9903635,0.006089111,0.0005499655,0.001436821,0.001291801,0.0002687526],"domain_scores_gemma":[0.9792293,0.01461008,0.0009762989,0.001888543,0.002736391,0.0005593409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01001848,0.0009139188,0.82141,0.0003904309,0.001714273,0.0005854125,0.002179903,0.009924479,0.05340736,0.0003439487,0.001072115,0.09803964],"study_design_scores_gemma":[0.0001942944,0.00786957,0.9495806,0.00003313196,0.0008059472,0.000634081,0.0004189707,0.02750016,0.01125623,0.0002969849,0.001337078,0.00007291733],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938929,0.0006131367,0.004145598,0.00006112408,0.00002314945,0.00005612672,0.0001994581,0.00005580808,0.0009526604],"genre_scores_gemma":[0.9939026,0.0002404598,0.004560761,0.00006769918,0.00003318901,0.00005515043,0.0006110541,0.00003473965,0.000494454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02338872,"threshold_uncertainty_score":0.1236929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02176292653976361,"score_gpt":0.2701543571723412,"score_spread":0.2483914306325775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}