{"id":"W2057643991","doi":"10.1080/02786110310001612272","title":"Novel disulfides as anticancer/antimalarial agents","year":2003,"lang":"en","type":"article","venue":"Sulfur Letters","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Allison University; Toronto General Hospital; University of Toronto","funders":"","keywords":"Plasmodium falciparum; Organosulfur compounds; Chemistry; Malaria; In vitro; Antifungal; Pharmacology; Cancer cell; Antimalarial Agent; IC50; Human skin; Cancer; Biochemistry; Biology; Microbiology; Immunology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001350749,0.000167282,0.0002012937,0.00001825933,0.0000954443,0.00004698577,0.0001775172,0.00009865831,0.003431237],"category_scores_gemma":[0.0003613735,0.0001263555,0.0001265916,0.00007653704,0.0001099555,0.00007384111,0.00003592817,0.0001523417,0.0001636608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004340526,"about_ca_system_score_gemma":0.00001825317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000974317,"about_ca_topic_score_gemma":0.000003071091,"domain_scores_codex":[0.9989446,0.00002509144,0.0001642796,0.0003359905,0.0001937695,0.0003362368],"domain_scores_gemma":[0.9994505,0.0001413399,0.00006848842,0.000239056,0.00001494971,0.00008567495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003113018,0.0001342522,0.01434705,0.00001314874,0.00003704545,0.00001619747,0.00001839838,0.000002633039,0.9817017,0.0005909251,0.001345817,0.001761735],"study_design_scores_gemma":[0.0006124655,0.0000153935,0.01139089,0.00002728313,0.00002811148,0.00002063662,0.00004780089,0.00001161362,0.9414615,0.0001767074,0.04588969,0.0003179217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97375,0.00002022154,0.0002302711,0.001600108,0.0002148074,0.00003923102,0.00002112409,0.00006955922,0.02405468],"genre_scores_gemma":[0.9965006,0.00001171258,0.0006041453,0.00235106,0.0002452296,0.000009777071,0.000007540334,0.00001407113,0.0002558918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04454387,"threshold_uncertainty_score":0.9974797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02514993199241167,"score_gpt":0.2490886646002394,"score_spread":0.2239387326078277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}