{"id":"W2057643991","doi":"10.1080/02786110310001612272","title":"Novel disulfides as anticancer/antimalarial agents","year":2003,"lang":"en","type":"article","venue":"Sulfur Letters","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Allison University; Toronto General Hospital; University of Toronto","funders":"","keywords":"Plasmodium falciparum; Organosulfur compounds; Chemistry; Malaria; In vitro; Antifungal; Pharmacology; Cancer cell; Antimalarial Agent; IC50; Human skin; Cancer; Biochemistry; Biology; Microbiology; Immunology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000130864,0.0002783078,0.0001859999,0.0001638036,0.0001156439,0.0001774535,0.0001843748,0.0002157514,0.0009340757],"category_scores_gemma":[0.00006132219,0.00008709044,0.0001410785,0.0001128878,0.0001218393,0.0001756285,0.000143469,0.0002562506,0.000291589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001321981,"about_ca_system_score_gemma":0.00008256595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009495609,"about_ca_topic_score_gemma":0.0002472918,"domain_scores_codex":[0.9999549,0.00001235707,0.000004603535,0.000008148323,0.00001154938,0.000008380818],"domain_scores_gemma":[0.9999672,0.000003698458,0.000007394092,0.000002757482,0.000007929102,0.00001090828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002312506,0.00006525294,0.0001725796,0.0001651743,0.00001297413,0.0001728451,0.00004063313,0.0003184701,0.9850891,0.0006757551,0.0002320519,0.01282397],"study_design_scores_gemma":[0.0000491237,0.001124693,0.0004428577,0.000009780297,0.00002292522,0.0003041271,0.0000226003,0.000585313,0.9829358,0.0001456804,0.01435195,0.000005121043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764214,0.01243682,0.004506323,0.0002397406,0.0001304646,0.00006626421,0.0001828016,0.0001231958,0.005893045],"genre_scores_gemma":[0.9826485,0.006767189,0.004830438,0.000126458,0.00006504826,0.00003059563,0.0003543384,0.00001802739,0.005159496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009340757,"threshold_uncertainty_score":0.003124774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02514993199241167,"score_gpt":0.2490886646002394,"score_spread":0.2239387326078277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}