{"id":"W2057671399","doi":"10.1016/j.stemcr.2014.04.008","title":"Primitive Neural Stem Cells in the Adult Mammalian Brain Give Rise to GFAP-Expressing Neural Stem Cells","year":2014,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Science Council; Heart and Stroke Foundation of Canada","keywords":"Biology; Neural stem cell; Forebrain; Embryonic stem cell; Neurosphere; Cell biology; Stem cell; Fibroblast growth factor; Population; Precursor cell; Leukemia inhibitory factor; Subependymal zone; Adult stem cell; Neuroscience; Cell; Genetics; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001110047,0.0002423428,0.0002452306,0.0004371077,0.0002476108,0.0003687471,0.0002169348,0.0002190775,0.001170449],"category_scores_gemma":[0.000171183,0.0001849314,0.0001403704,0.0002153603,0.0003346469,0.0002368529,0.000350475,0.0003682965,0.0009719761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001397722,"about_ca_system_score_gemma":0.0002368815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000494843,"about_ca_topic_score_gemma":0.0008649378,"domain_scores_codex":[0.9998997,0.000006009641,0.00001126793,0.00002235806,0.00004913923,0.00001138684],"domain_scores_gemma":[0.9998972,0.00001164436,0.00002453711,0.0000129785,0.00002015778,0.00003344097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001422372,0.00002235734,0.005068417,0.0001882008,0.00001091396,0.0008949483,0.0002444633,0.0002090672,0.9561459,0.002420058,0.0003005723,0.0343527],"study_design_scores_gemma":[0.00002318013,0.0003953253,0.0535915,0.00008528288,0.00005212025,0.005999144,0.0003231137,0.0009080043,0.890259,0.002811403,0.04552784,0.00002422259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9335428,0.01450731,0.03286014,0.0001884276,0.000100007,0.0001092292,0.001384173,0.0006434012,0.0166644],"genre_scores_gemma":[0.9550798,0.0103902,0.02001122,0.00009476751,0.00005965375,0.0000840927,0.001937749,0.00005444293,0.01228804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001170449,"threshold_uncertainty_score":0.003915548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02416059591953891,"score_gpt":0.2371352774235794,"score_spread":0.2129746815040405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}