{"id":"W2057672138","doi":"10.1038/sj.mt.6300215","title":"Targeted Inflammation During Oncolytic Virus Therapy Severely Compromises Tumor Blood Flow","year":2007,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":277,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"Oncolytic virus; Inflammation; Virus; Medicine; Immunology; Virology; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002052682,0.0002836348,0.000268753,0.0001112573,0.0001041773,0.0003425084,0.0001140631,0.0002614452,0.0005015655],"category_scores_gemma":[0.0001336798,0.0001081566,0.0001679526,0.00008533121,0.0002341711,0.0002432878,0.000163909,0.0006829944,0.000126631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003177511,"about_ca_system_score_gemma":0.0002994873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003485358,"about_ca_topic_score_gemma":0.0005019231,"domain_scores_codex":[0.9997875,0.00004206426,0.00001604912,0.00004638017,0.00004408163,0.00006393015],"domain_scores_gemma":[0.9999352,0.00001658342,0.00002487848,0.000006356212,0.000005066329,0.00001180844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001628749,0.00003199003,0.0001474304,0.00002524598,0.000002572456,0.00002094179,0.00001727415,0.0001118608,0.9981041,0.0001286312,0.00002010119,0.001226934],"study_design_scores_gemma":[0.00002100032,0.001033886,0.001176485,0.000005622034,0.00001009428,0.0001625105,0.00001831171,0.001394423,0.9948735,0.00007447051,0.001226719,0.000002976321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993846,0.001431459,0.003854503,0.00006191325,0.00002806561,0.00004398856,0.0001029679,0.00003982898,0.0005913691],"genre_scores_gemma":[0.9958901,0.0005413024,0.002435811,0.0000411995,0.000009096319,0.00005584763,0.0001058371,0.000007343326,0.0009133868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005015655,"threshold_uncertainty_score":0.002305448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01298807240059896,"score_gpt":0.273092995067845,"score_spread":0.2601049226672461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}