{"id":"W2057677145","doi":"10.1006/dbio.2001.0231","title":"Human Cytotrophoblast Expression of the von Hippel–Lindau Protein Is Downregulated during Uterine Invasion in Situ and Upregulated by Hypoxia in Vitro","year":2001,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health; McMaster University","keywords":"Cytotrophoblast; Biology; Oxygen tension; Downregulation and upregulation; Cell biology; Placenta; Hypoxia (environmental); Fetus; Chemistry; Biochemistry; Oxygen","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001146108,0.0001975213,0.0002522224,0.00008989062,0.00007000244,0.000007085628,0.0001795189,0.0002573655,0.00002457829],"category_scores_gemma":[0.00001734657,0.0001562003,0.00004245061,0.0001878526,0.0001458375,0.000007057281,0.0003262275,0.000124464,0.000001377201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000428153,"about_ca_system_score_gemma":0.00004949706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001328514,"about_ca_topic_score_gemma":0.0001777681,"domain_scores_codex":[0.9987396,0.00009957309,0.0003715034,0.0004180992,0.00007191223,0.0002992994],"domain_scores_gemma":[0.9996079,0.000003552618,0.0001208603,0.0001917979,0.00002461148,0.00005127171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000351873,0.00006807019,0.005876862,0.0000202303,0.00001072705,0.000001675969,0.000167147,0.000001328976,0.9918671,0.000001919086,0.00008228781,0.001550786],"study_design_scores_gemma":[0.001625083,0.00005544462,0.1085398,0.00005706952,0.000002364837,0.00003007046,0.0000481503,0.000002380577,0.8848418,0.00002783478,0.004599918,0.0001701335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998555,0.0007297166,0.000004558794,0.00006271811,0.0001209926,0.0003870982,0.00003090331,0.000007418742,0.0001015961],"genre_scores_gemma":[0.9986956,0.0002585117,0.0002166875,0.00007988993,0.00006164135,0.00003817231,0.0001593439,0.00001666777,0.0004735617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1070253,"threshold_uncertainty_score":0.6369663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006601157898133863,"score_gpt":0.2249669167172389,"score_spread":0.218365758819105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}