{"id":"W2057683153","doi":"10.1089/jop.2009.0031","title":"Benzalkonium Chloride Enhances Antibacterial Activity of Gatifloxacin and Reduces its Propensity to Select for Fluoroquinolone-Resistant Strains","year":2009,"lang":"en","type":"article","venue":"Journal of Ocular Pharmacology and Therapeutics","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal University Hospital","funders":"","keywords":"Gatifloxacin; Moxifloxacin; Levofloxacin; Benzalkonium chloride; Staphylococcus aureus; Microbiology; Medicine; Minimum inhibitory concentration; Chemistry; Pharmacology; Antimicrobial; Antibiotics; Chromatography; Biology; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004376528,0.0001613817,0.0005185866,0.0001227194,0.00009091293,0.00001726697,0.00008462154,0.0001038166,0.00001268954],"category_scores_gemma":[0.00002457838,0.0001263217,0.00009447094,0.0001061491,0.0001011041,0.00008292984,0.00002222606,0.0002396447,2.773194e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001921991,"about_ca_system_score_gemma":0.0001255055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000103465,"about_ca_topic_score_gemma":6.304006e-7,"domain_scores_codex":[0.999018,0.00006531319,0.0003704975,0.0001619497,0.000154181,0.0002300386],"domain_scores_gemma":[0.9990583,0.00006288807,0.0003139484,0.00006278179,0.0003394191,0.0001626423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006102121,0.0003864556,0.0002107736,0.00009203806,0.0004561394,0.00003060024,0.0002793927,0.000007399163,0.976999,0.00006151196,0.00007127575,0.01530325],"study_design_scores_gemma":[0.003116347,0.003931268,0.03036142,0.00006812058,0.0008014343,0.0001168842,0.00002178773,0.0002408024,0.9594445,0.0001112118,0.001665778,0.0001204587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943305,0.001205632,0.0004078148,0.003160393,0.0003679705,0.0004770136,0.00001595421,0.000006234776,0.00002850875],"genre_scores_gemma":[0.9954398,0.002227717,0.001103421,0.0008194701,0.0003698062,7.310676e-7,0.000001583884,0.00001158632,0.00002593243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03015064,"threshold_uncertainty_score":0.5151248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03831685265093232,"score_gpt":0.3471052119290933,"score_spread":0.308788359278161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}