{"id":"W2057726273","doi":"10.1002/cyto.a.20878","title":"Human ESC colony formation is dependent on interplay between self‐renewing hESCs and unique precursors responsible for niche generation","year":2010,"lang":"en","type":"article","venue":"Cytometry Part A","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute; University of Waterloo","funders":"","keywords":"Paracrine signalling; Biology; Embryonic stem cell; Cell biology; Flow cytometry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006561228,0.0001482207,0.0001424908,0.0001882237,0.0002088083,0.00007719331,0.0001667211,0.0002532462,0.00001726192],"category_scores_gemma":[0.0001353945,0.0001453321,0.00005760425,0.0001356488,0.00003916668,0.00001598168,0.0001142592,0.0001907686,0.00001150125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003318328,"about_ca_system_score_gemma":0.00006483591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006902412,"about_ca_topic_score_gemma":0.00008296961,"domain_scores_codex":[0.9988629,0.0000915185,0.0002296621,0.0003568927,0.000186011,0.0002729675],"domain_scores_gemma":[0.9993247,0.00004534944,0.00008478944,0.0003217709,0.0001084281,0.0001149762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007052483,0.00004431369,0.004398268,0.0000430808,0.00005257355,9.138509e-7,0.0001136971,0.00000704692,0.9878936,0.00004402471,0.006389563,0.0009423462],"study_design_scores_gemma":[0.0005655214,0.000570204,0.002257911,0.00001639519,0.00002357199,0.000007633984,0.00002445237,0.000474274,0.964707,0.00004201756,0.03114503,0.0001659958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963109,0.00006264736,0.002114957,0.0001767827,0.0001138006,0.0005518893,0.00006022857,0.00002272544,0.0005860681],"genre_scores_gemma":[0.996491,0.00003528992,0.001097653,0.0001486972,0.0003932578,0.00009902092,0.0003526214,0.00002491609,0.00135753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02475547,"threshold_uncertainty_score":0.5926471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03347472527469485,"score_gpt":0.3477492333482007,"score_spread":0.3142745080735058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}