{"id":"W2057726273","doi":"10.1002/cyto.a.20878","title":"Human ESC colony formation is dependent on interplay between self‐renewing hESCs and unique precursors responsible for niche generation","year":2010,"lang":"en","type":"article","venue":"Cytometry Part A","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute; University of Waterloo","funders":"","keywords":"Paracrine signalling; Biology; Embryonic stem cell; Cell biology; Flow cytometry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001066408,0.0001696288,0.0001457192,0.0001334377,0.00008947024,0.0002637081,0.00006646328,0.00007007402,0.0006863497],"category_scores_gemma":[0.000111805,0.0001069639,0.00008776691,0.0001015069,0.0001109617,0.0001171668,0.0001948189,0.000163408,0.000381449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001344958,"about_ca_system_score_gemma":0.000121193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003032615,"about_ca_topic_score_gemma":0.0005001304,"domain_scores_codex":[0.9999332,0.000007602951,0.000005597528,0.00001291881,0.00003092353,0.00000970818],"domain_scores_gemma":[0.9999363,0.00001464929,0.000008815266,0.00001317106,0.0000127874,0.00001427179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002755713,0.000005043956,0.0004645545,0.000007535517,0.000001870892,0.00004742403,0.00001289152,0.00002500768,0.9974619,0.00008247833,0.00002452714,0.001839085],"study_design_scores_gemma":[0.000008030789,0.00008894179,0.02607594,0.000005694867,0.00001201249,0.0007285721,0.00002941404,0.001282697,0.9684254,0.0001320665,0.003207834,0.000003446685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925963,0.001290657,0.003832571,0.00003098794,0.000005637331,0.0000170326,0.0001775969,0.00007093358,0.001978195],"genre_scores_gemma":[0.9948913,0.0007652832,0.002198837,0.00002001216,0.000005907239,0.00001600934,0.0003873835,0.00002235474,0.001692911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006863497,"threshold_uncertainty_score":0.00229609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03347472527469485,"score_gpt":0.3477492333482007,"score_spread":0.3142745080735058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}