{"id":"W2057734107","doi":"10.1016/j.eururo.2009.06.027","title":"Castration-resistant Prostate Cancer: From New Pathophysiology to New Treatment Targets","year":2009,"lang":"en","type":"review","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":255,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Princess Margaret Cancer Centre; BC Cancer Agency","funders":"Cancer Research UK","keywords":"Medicine; Prostate cancer; Clinical trial; Oncology; Androgen receptor; Immunotherapy; Internal medicine; Bevacizumab; Bioinformatics; Cancer; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000111366,0.0007364047,0.002107923,0.0002858573,0.00009780464,0.00003574409,0.0002786057,0.0002194404,0.0006792674],"category_scores_gemma":[0.00005146414,0.000497672,0.0004560014,0.0003221809,0.00007217913,0.0000366516,0.0001041963,0.0004452221,0.001798283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005461594,"about_ca_system_score_gemma":0.002626299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002107692,"about_ca_topic_score_gemma":0.0002269401,"domain_scores_codex":[0.9965424,0.0006148561,0.0007164662,0.001104774,0.0002243814,0.0007971553],"domain_scores_gemma":[0.9978811,0.0001351838,0.0002590519,0.0007533053,0.00006948267,0.0009019212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006834059,0.0001454462,0.000008414123,0.0003003552,0.0005460436,0.0022543,0.0004035507,0.000004403684,0.0001369197,0.000009760258,0.02930743,0.9662],"study_design_scores_gemma":[0.002053677,0.004767898,0.0003332506,0.0008722796,0.001477053,0.00003836992,0.000005243756,6.364646e-7,0.00001124445,0.0001300499,0.9899594,0.0003508772],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001367063,0.9912155,0.00001543293,0.002550098,0.0004571811,0.002371673,0.0003511268,0.0001207686,0.002781522],"genre_scores_gemma":[0.000019081,0.9596655,0.0006200611,0.001160162,0.002220385,0.00008933443,0.001642181,0.0001422236,0.0344411],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9658491,"threshold_uncertainty_score":0.9997475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06359432475833031,"score_gpt":0.3659656362270145,"score_spread":0.3023713114686842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}