{"id":"W2057734107","doi":"10.1016/j.eururo.2009.06.027","title":"Castration-resistant Prostate Cancer: From New Pathophysiology to New Treatment Targets","year":2009,"lang":"en","type":"review","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":255,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Princess Margaret Cancer Centre; BC Cancer Agency","funders":"Cancer Research UK","keywords":"Medicine; Prostate cancer; Clinical trial; Oncology; Androgen receptor; Immunotherapy; Internal medicine; Bevacizumab; Bioinformatics; Cancer; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000838903,0.00108909,0.002650177,0.001993279,0.0003132982,0.001375471,0.0009997946,0.001180801,0.003205555],"category_scores_gemma":[0.0008820024,0.0003750896,0.0005496041,0.002709621,0.0008769772,0.001869453,0.0008034269,0.002205856,0.001723269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009608952,"about_ca_system_score_gemma":0.00213541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001391422,"about_ca_topic_score_gemma":0.003406557,"domain_scores_codex":[0.9997197,0.0000501351,0.0000396094,0.00005060257,0.0001125966,0.00002736088],"domain_scores_gemma":[0.9995112,0.0002390214,0.00007013043,0.00001390942,0.0001243526,0.00004124659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001252099,0.0001027734,0.0002600622,0.01600086,0.0001395265,0.0002548213,0.00004542077,0.0004966174,0.001234476,0.003162859,0.04500817,0.9331692],"study_design_scores_gemma":[0.00006455679,0.0001197185,0.001138086,0.003488934,0.0002196406,0.001499126,0.00009352261,0.0001493334,0.0003473338,0.002189998,0.990661,0.00002867068],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006060272,0.9988739,0.0000802173,0.000318548,0.0002087197,0.000002409427,0.0000102174,0.000005429837,0.0004399443],"genre_scores_gemma":[0.0004520879,0.9987167,0.0001224393,0.0002265834,0.000207208,0.000002871338,0.00001780153,8.079796e-7,0.0002535432],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003205555,"threshold_uncertainty_score":0.01072371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06359432475833031,"score_gpt":0.3659656362270145,"score_spread":0.3023713114686842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}