{"id":"W2057855349","doi":"10.1016/j.expneurol.2012.11.013","title":"Selectively reducing cytokine/chemokine expressing macrophages in injured nerves impairs the development of neuropathic pain","year":2012,"lang":"en","type":"article","venue":"Experimental Neurology","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University; AstraZeneca","keywords":"Wallerian degeneration; Neuropathic pain; Chemokine; Sciatic nerve; Medicine; Cytokine; Inflammation; Population; Nerve injury; Peripheral nerve injury; Microglia; Immunology; Pathology; Neuroscience; Anatomy; Biology; Anesthesia","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002555609,0.0005076966,0.0006177771,0.0003780914,0.0003005433,0.0004109706,0.0003803237,0.0005806114,0.002288268],"category_scores_gemma":[0.0001793694,0.0002502256,0.000297148,0.0001698667,0.0005780443,0.0003716823,0.0002350944,0.001138773,0.000515554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002355316,"about_ca_system_score_gemma":0.0004618691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004082756,"about_ca_topic_score_gemma":0.0009212773,"domain_scores_codex":[0.9997072,0.00005026694,0.00002414768,0.00003940703,0.00005943517,0.0001194558],"domain_scores_gemma":[0.9998291,0.00002170852,0.00004461348,0.00001637827,0.00001873645,0.00006954675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009105206,0.0001941837,0.00008219214,0.00004227775,0.000005503517,0.00004996347,0.00001758965,0.00004965477,0.9972576,0.0001233444,0.00004053388,0.001226652],"study_design_scores_gemma":[0.0001572177,0.002793502,0.002315979,0.00001840728,0.0000464226,0.000329337,0.00008977946,0.0005742143,0.9925142,0.0001377767,0.001014794,0.000008370429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963369,0.001084115,0.001323053,0.0001560433,0.00007063994,0.00003389619,0.00008123996,0.00005051298,0.000863571],"genre_scores_gemma":[0.9930193,0.001319723,0.002142203,0.0001078017,0.00004543512,0.00007219429,0.000133143,0.00002597822,0.003134256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002288268,"threshold_uncertainty_score":0.007655084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02117792231529285,"score_gpt":0.2940627291917027,"score_spread":0.2728848068764099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}