{"id":"W2057937016","doi":"10.1530/rep-12-0237","title":"Genomic imprints as a model for the analysis of epigenetic stability during assisted reproductive technologies","year":2012,"lang":"en","type":"review","venue":"Reproduction","topic":"Reproductive Health and Technologies","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Epigenetics; Genomic imprinting; DNA methylation; Biology; Oocyte; Infertility; Germline; Genetics; Genome instability; Reprogramming; Gamete; Embryo; Sperm; Gene; Pregnancy; Gene expression; DNA damage; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002379531,0.0005489399,0.002853002,0.001132041,0.0002738271,0.00001535691,0.0004096596,0.0006216205,0.00001711273],"category_scores_gemma":[0.005312956,0.0003591215,0.001280313,0.002593344,0.0005742358,0.0001027714,0.0002856987,0.0007572273,0.00001249773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006916509,"about_ca_system_score_gemma":0.0005315866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006429198,"about_ca_topic_score_gemma":0.000007359693,"domain_scores_codex":[0.9951587,0.0001339312,0.001398094,0.002339638,0.0003709415,0.0005987328],"domain_scores_gemma":[0.9918025,0.0002103613,0.001402825,0.005861564,0.0006569287,0.00006586376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001741146,0.0002611385,0.0003197659,0.01724576,0.00385423,8.568604e-7,0.0001520513,0.0000847933,0.0007349518,0.00009996475,0.000009388723,0.977063],"study_design_scores_gemma":[0.001938989,0.001122718,0.05190402,0.005743927,0.2644173,0.001275511,0.002797472,0.002438087,0.03608599,0.003774308,0.6254357,0.00306593],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01480834,0.9766205,0.0008337178,0.0006670972,0.0004332501,0.005942427,0.00006451149,0.0005893763,0.0000407688],"genre_scores_gemma":[0.04772055,0.9479947,0.001737462,0.000002668699,0.0003833816,0.001567238,0.00009224663,0.00007706953,0.0004246554],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9739971,"threshold_uncertainty_score":0.9998861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1741594172428937,"score_gpt":0.3967731960092171,"score_spread":0.2226137787663233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}