{"id":"W2057952486","doi":"10.1080/14786419.2014.979423","title":"Natural product extracts of the Canadian prairie plant,<i>Thermopsis rhombifolia,</i>have anti-cancer activity in phenotypic cell-based assays","year":2014,"lang":"en","type":"article","venue":"Natural Product Research","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Johns Hopkins University","keywords":"Biology; Cancer; Natural product; Cancer cell; Phenotype; Botany; Cancer cell lines; Cytotoxicity; Biochemistry; In vitro; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.003964723,0.0004472628,0.0007561184,0.0007129502,0.0005263615,0.0000965161,0.0008352377,0.0002706936,0.0001819146],"category_scores_gemma":[0.004215774,0.0002782043,0.0002242057,0.001759548,0.0007075287,0.0002570393,0.000195634,0.003645238,0.00002897332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008166223,"about_ca_system_score_gemma":0.002176509,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.07924163,"about_ca_topic_score_gemma":0.1586239,"domain_scores_codex":[0.9940962,0.001031421,0.0005166635,0.001285503,0.001597577,0.001472673],"domain_scores_gemma":[0.9964002,0.0003867965,0.0002388142,0.001460785,0.001183277,0.0003301721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007248367,0.0003939519,0.01507752,0.000718303,0.00005732646,0.00001763163,0.0001599347,0.00002905858,0.945045,0.00005439939,0.01594535,0.0217767],"study_design_scores_gemma":[0.000946851,0.0001065852,0.1540582,0.0002867272,0.00004156352,0.00001622921,0.00001993828,0.0004125854,0.8280888,0.00004835727,0.01565355,0.0003206162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9420038,0.003437353,2.902936e-7,0.04918961,0.0009431257,0.00236723,0.00007874016,0.00004412828,0.001935691],"genre_scores_gemma":[0.9929945,0.0000608619,0.0001381515,0.0004391013,0.001043165,0.00001759534,0.00004633192,0.00006485786,0.005195379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1389807,"threshold_uncertainty_score":0.999967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03862533390398876,"score_gpt":0.3219718182441246,"score_spread":0.2833464843401359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}