{"id":"W2057960189","doi":"10.1016/j.cjca.2014.07.164","title":"EFFECT OF MACITENTAN ON HEMODYNAMICS IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION: Results FROM THE LONG-TERM, RANDOMISED, PLACEBO-CONTROLLED SERAPHIN TRIAL","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Calgary Laboratory Services","funders":"","keywords":"Medicine; Pulmonary hypertension; Vascular resistance; Placebo; Internal medicine; Cardiology; Cardiac index; Endothelin receptor antagonist; Hemodynamics; Blood pressure; Central venous pressure; Anesthesia; Endothelin receptor; Cardiac output; Heart rate","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001338162,0.001393667,0.003752441,0.0002369267,0.0003550168,0.001093815,0.0008936236,0.0014405,0.003578506],"category_scores_gemma":[0.002014187,0.0004260422,0.002072411,0.0002718364,0.0009403366,0.001013554,0.0003564736,0.003143322,0.000545813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007047598,"about_ca_system_score_gemma":0.0006125762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001304915,"about_ca_topic_score_gemma":0.003067481,"domain_scores_codex":[0.9994166,0.0003033601,0.0000478261,0.00008967027,0.00004281033,0.00009985723],"domain_scores_gemma":[0.9990645,0.000318541,0.0002131983,0.00009022015,0.00005719476,0.0002563839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9839984,0.001006156,0.001070391,0.0007741328,0.00173912,0.00004937493,0.00003515926,0.0001407698,0.001591547,0.00007738169,0.0003976522,0.009119914],"study_design_scores_gemma":[0.9514559,0.03109082,0.01276262,0.0001314762,0.002558738,0.00006708912,0.00008371157,0.0004191419,0.0004080109,0.000211335,0.000777975,0.00003328334],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806737,0.01510016,0.0002880856,0.0008338237,0.0006042028,0.0002747363,0.0006307443,0.0000631123,0.001531403],"genre_scores_gemma":[0.9906245,0.005125496,0.0003833874,0.000796044,0.0004985238,0.0003221755,0.0006742273,0.00001294594,0.00156281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003752441,"threshold_uncertainty_score":0.01197129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008460177050189569,"score_gpt":0.2267873343329928,"score_spread":0.2183271572828032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}