{"id":"W2057969646","doi":"10.1038/sj.gene.6363911","title":"Segregation of HLA/TNF region is linked to leprosy clinical spectrum in families displaying mixed leprosy subtypes","year":2003,"lang":"en","type":"article","venue":"Genes and Immunity","topic":"Leprosy Research and Treatment","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill Genome Centre","funders":"","keywords":"Leprosy; Lepromatous leprosy; Biology; Immunology; Human leukocyte antigen; Disease; Haplotype; Mycobacterium leprae; Genetic linkage; Pathogenesis; Genetics; Allele; Medicine; Antigen; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004099589,0.0007018406,0.000469942,0.001787378,0.001179855,0.0006380028,0.0005477719,0.0006559823,0.006629157],"category_scores_gemma":[0.001801222,0.0003907886,0.00038368,0.0008413607,0.0005511191,0.0003290372,0.0005546274,0.0005236801,0.000533778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002526476,"about_ca_system_score_gemma":0.0002079852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001962734,"about_ca_topic_score_gemma":0.00111676,"domain_scores_codex":[0.9993516,0.0001810278,0.00008361782,0.0001483572,0.00007937082,0.0001560638],"domain_scores_gemma":[0.9983243,0.0005914246,0.0005158217,0.00008410437,0.0001104441,0.0003739567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006118421,0.0004282508,0.8490441,0.00004989696,0.0001921432,0.02229462,0.002184444,0.0002198662,0.112914,0.0004313464,0.0002071219,0.005915908],"study_design_scores_gemma":[0.0000856064,0.0005940432,0.9474466,0.00003324093,0.0001285926,0.04575163,0.001241328,0.0005716662,0.003533292,0.000209656,0.0003839684,0.00002023021],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995303,0.00005568759,0.00007556349,0.00001641055,0.000001918388,0.000002667153,0.00004509904,0.000003453462,0.000268949],"genre_scores_gemma":[0.9996467,0.00002160836,0.00008326646,0.00001007036,0.000005762396,0.000003032226,0.00004811406,0.000004437705,0.000177131],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006629157,"threshold_uncertainty_score":0.0221768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06025774853986444,"score_gpt":0.3479026162569378,"score_spread":0.2876448677170734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}