{"id":"W2057969646","doi":"10.1038/sj.gene.6363911","title":"Segregation of HLA/TNF region is linked to leprosy clinical spectrum in families displaying mixed leprosy subtypes","year":2003,"lang":"en","type":"article","venue":"Genes and Immunity","topic":"Leprosy Research and Treatment","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill Genome Centre","funders":"","keywords":"Leprosy; Lepromatous leprosy; Biology; Immunology; Human leukocyte antigen; Disease; Haplotype; Mycobacterium leprae; Genetic linkage; Pathogenesis; Genetics; Allele; Medicine; Antigen; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005593385,0.000129036,0.0003350035,0.0001359394,0.00009798649,0.00001754758,0.00005898123,0.00009890143,0.00001944825],"category_scores_gemma":[0.000240721,0.0001002128,0.00007776057,0.0002534945,0.00009016503,0.00007278967,0.00005808169,0.000219132,0.00001248763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004463625,"about_ca_system_score_gemma":0.0001045331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001215695,"about_ca_topic_score_gemma":0.0002528332,"domain_scores_codex":[0.9988091,0.0001690658,0.000353881,0.0002435133,0.0001735645,0.0002508817],"domain_scores_gemma":[0.9992446,0.00009945677,0.00006716557,0.0003827192,0.00006907572,0.0001370146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003884321,0.0004130509,0.953854,0.0001153509,0.00006127918,0.00001872925,0.0006657285,0.000002090954,0.005615319,0.0004216579,0.00007217129,0.03837225],"study_design_scores_gemma":[0.002118203,0.0009297938,0.9614472,0.000111102,0.00003508883,0.00002552807,0.0006938012,0.00007661023,0.03198543,0.0005662012,0.001902004,0.000108972],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965515,0.001318149,0.00008035412,0.0007505302,0.00008708605,0.0005209237,0.00000592392,0.00001459055,0.0006710007],"genre_scores_gemma":[0.9965577,0.002413846,0.0005032771,0.0001124524,0.00003117855,0.00002209927,0.00002109742,0.0000120794,0.0003262508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03826328,"threshold_uncertainty_score":0.4086561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06025774853986444,"score_gpt":0.3479026162569378,"score_spread":0.2876448677170734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}