{"id":"W2057999664","doi":"10.1126/stke.2712005re2","title":"Protein Interfaces in Signaling Regulated by Arginine Methylation","year":2005,"lang":"en","type":"review","venue":"Science s STKE","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Methylation; Arginine; Protein arginine methyltransferase 5; Signal transduction; Protein methylation; Biology; Biochemistry; Cell biology; Methyltransferase; Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000844478,0.0002855757,0.0004672317,0.0002869614,0.0000896097,0.00006531749,0.0004591726,0.000349715,0.00003472672],"category_scores_gemma":[0.0001183039,0.0002590122,0.0001125887,0.001039744,0.0002637825,0.00001680497,0.0001387685,0.0002183886,0.00002025507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002052385,"about_ca_system_score_gemma":0.0005842678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001978293,"about_ca_topic_score_gemma":0.00003601626,"domain_scores_codex":[0.9979365,0.0001046886,0.000506399,0.0007613713,0.0003257935,0.0003652668],"domain_scores_gemma":[0.9990817,0.000009195636,0.0003301976,0.0004096895,0.00009350399,0.0000756653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006283365,0.0000175329,6.005174e-7,0.0002245137,0.00001402326,3.286333e-7,0.00001755685,0.0003070334,0.2014631,0.00000931344,0.0001607793,0.797779],"study_design_scores_gemma":[0.0001736534,0.00009385791,0.000002849247,0.002037673,0.00004391222,0.000007676465,0.000009787035,0.000197083,0.07096087,0.00001963864,0.9260831,0.0003698495],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007192029,0.991173,0.0002653731,0.00003889813,0.0001742231,0.0008434803,0.0000206487,0.00001876566,0.000273633],"genre_scores_gemma":[0.0121709,0.984597,0.0005951563,0.00001096749,0.000271844,0.0001058024,0.0003521218,0.00004274707,0.001853512],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9259224,"threshold_uncertainty_score":0.9999862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02069367799090047,"score_gpt":0.3299227910756448,"score_spread":0.3092291130847443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}