{"id":"W2058001278","doi":"10.1242/jcs.02601","title":"Cholesterol facilitates the native mechanism of Ca2+-triggered membrane fusion","year":2005,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":177,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Calgary","funders":"","keywords":"Exocytosis; Membrane; Lipid bilayer fusion; Biology; Membrane curvature; Vesicle; Fusion; Vesicle fusion; Biophysics; Kinetics; Biochemistry; Cell biology; Cholesterol; Synaptic vesicle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006490051,0.00008397153,0.0001236729,0.00006131752,0.00009856446,0.00001985388,0.0004748495,0.00004727148,0.00002830182],"category_scores_gemma":[0.00006957292,0.00004719855,0.00008972509,0.0001609735,0.0002617597,0.00001893042,0.00007531963,0.0001072893,0.000001842191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001395562,"about_ca_system_score_gemma":0.0001688149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000456825,"about_ca_topic_score_gemma":0.00000739687,"domain_scores_codex":[0.9990317,0.00003570177,0.0002671012,0.000129751,0.000379682,0.0001560964],"domain_scores_gemma":[0.9991697,0.00001418483,0.0002751253,0.0001741242,0.0002939572,0.00007292245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001838926,0.00003125563,0.00002657668,0.000005392058,0.000003857477,6.101982e-7,0.0002766971,0.00004222629,0.9977454,0.00002554093,0.00005855986,0.001765479],"study_design_scores_gemma":[0.0003483746,0.0002591508,0.0004628825,0.000008778671,0.00001770126,0.0000468529,0.0001788818,0.00003116298,0.9951276,0.00001696429,0.003443955,0.00005772287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983631,0.00009585775,0.0001904818,0.0002918641,0.0002476863,0.00007418688,0.000005068644,0.000001108538,0.0007306839],"genre_scores_gemma":[0.9986105,0.0001157733,0.000497348,0.0001267269,0.0002573175,6.878667e-7,7.872516e-7,0.000003748801,0.0003870892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003385395,"threshold_uncertainty_score":0.1924701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008549899932183304,"score_gpt":0.247754007301642,"score_spread":0.2392041073694587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}