{"id":"W2058005021","doi":"10.1139/cjpp-78-4-267","title":"Cardiovascular α<sub>1</sub>-adrenoceptor subtypes: functions and signaling","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Phospholipase C; Endocrinology; Vasoconstriction; Internal medicine; Biology; Protein kinase C; G protein; Receptor; Adrenergic receptor; Signal transduction; Inotrope; Cell biology; Protein kinase A; Intracellular; Alpha (finance); Kinase; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001038292,0.0003560492,0.0002700082,0.0002386629,0.0002582252,0.0004974012,0.0002414408,0.0003147037,0.00564717],"category_scores_gemma":[0.00008667379,0.0001290431,0.0001827733,0.0002469374,0.000239254,0.0002575193,0.0002198345,0.0005243864,0.00220186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005489431,"about_ca_system_score_gemma":0.0002696725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001913993,"about_ca_topic_score_gemma":0.001917498,"domain_scores_codex":[0.9999249,0.000006042303,0.000004085795,0.00001703081,0.0000221269,0.00002581564],"domain_scores_gemma":[0.9999452,0.000002264417,0.000009263333,0.000004011324,0.0000145845,0.00002466931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007121204,0.00007046907,0.00321563,0.0002956115,0.00002668424,0.0003719662,0.00008758508,0.0002525398,0.912243,0.002990422,0.003919661,0.07581435],"study_design_scores_gemma":[0.0002878246,0.00176905,0.2783623,0.0002876545,0.0002758596,0.006896687,0.0003990139,0.003680401,0.4549035,0.007610512,0.2454325,0.00009469705],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.776242,0.08731322,0.02025901,0.004364129,0.001133265,0.0001865342,0.003549714,0.0008647039,0.1060874],"genre_scores_gemma":[0.9033958,0.03655357,0.005306845,0.0008940099,0.0005172985,0.00007030776,0.002293613,0.00008338057,0.05088526],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.00564717,"threshold_uncertainty_score":0.01889169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007404032037804879,"score_gpt":0.2124322879672435,"score_spread":0.2050282559294386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}