{"id":"W2058009648","doi":"10.1016/s0957-4166(00)00242-1","title":"Synthesis and applications of (1R,5S,6S)-6-(2,2-dimethylpropanamido)spiro[4.4]nonan-1-ol as a chiral auxiliary in Diels–Alder reactions","year":2000,"lang":"en","type":"article","venue":"Tetrahedron Asymmetry","topic":"Analytical Chemistry and Chromatography","field":"Chemistry","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Diels–Alder reaction; Adduct; Chiral auxiliary; Derivative (finance); Chemistry; Alder; Stereochemistry; Absolute configuration; Organic chemistry; Catalysis; Enantioselective synthesis; Biology; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000197374,0.0003514776,0.000505281,0.0001987691,0.0001416611,0.00003224143,0.0003379819,0.0003634156,0.005379423],"category_scores_gemma":[0.0001281453,0.0003570144,0.0002325864,0.0008600237,0.0003868397,0.0001598639,0.00005913372,0.0005446105,0.00008761733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007778274,"about_ca_system_score_gemma":0.00007541804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004495466,"about_ca_topic_score_gemma":0.0000325184,"domain_scores_codex":[0.9978134,0.00003565928,0.0006922443,0.0006244237,0.0003575504,0.0004767273],"domain_scores_gemma":[0.9984716,0.0003835231,0.000157843,0.0006843032,0.0000461784,0.0002566069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006364889,0.006258344,0.1394653,0.005014877,0.001296197,0.0002126084,0.0006236056,0.0001154827,0.3030079,0.01374225,0.001939757,0.5276872],"study_design_scores_gemma":[0.002250378,0.0001314752,0.02361418,0.0007497044,0.0006438256,0.0002721364,0.001801159,0.001193942,0.8843795,0.01113017,0.07187221,0.001961301],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6929672,0.0009300484,0.00007983929,0.0001838159,0.00001675371,0.0001640247,0.00006769997,0.0001507701,0.3054399],"genre_scores_gemma":[0.9905434,0.0003155447,0.0004031943,0.0000860396,0.0001251327,0.0001585589,0.00003294359,0.00004610664,0.00828909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5813716,"threshold_uncertainty_score":0.9998882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005476621257400568,"score_gpt":0.2347449939696742,"score_spread":0.2292683727122737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}