{"id":"W2058045419","doi":"10.3390/v6114505","title":"Cholesterol Balance in Prion Diseases and Alzheimer’s Disease","year":2014,"lang":"en","type":"review","venue":"Viruses","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Alberta Prion Research Institute","keywords":"Lipid raft; Cholesterol; Endosome; Cell biology; Biology; Glycoprotein; Gene isoform; Homeostasis; Biochemistry; Cell; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008927005,0.0003330539,0.0005954726,0.00008067338,0.00004880628,0.000058685,0.0002289839,0.0001723423,0.00001787365],"category_scores_gemma":[0.0001135803,0.0002866727,0.0001965389,0.0000785571,0.00006664348,0.000006190942,0.0002101495,0.0001078108,0.00002262489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001073061,"about_ca_system_score_gemma":0.0001346492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001394217,"about_ca_topic_score_gemma":0.000005110459,"domain_scores_codex":[0.9986226,0.0001626531,0.0003148723,0.0005495435,0.0001068416,0.0002434907],"domain_scores_gemma":[0.9990957,0.00002799516,0.0001634253,0.0004499722,0.00001486084,0.0002480613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002596065,0.00004769569,0.001889012,0.002732985,0.00006408479,0.000006158928,0.000001736325,0.000001134703,0.00002752139,0.00002448019,0.0005005138,0.9946787],"study_design_scores_gemma":[0.0002005236,0.00003846759,0.001379064,0.002781466,0.0003777395,0.000003280308,9.158128e-7,0.000003876989,0.00001743395,0.00002066763,0.9948348,0.0003417812],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007385617,0.9983592,0.00001830721,0.00001189441,0.0000971073,0.0005118413,0.0002274835,0.00001668964,0.00001888908],"genre_scores_gemma":[0.001242846,0.9975627,0.00002689968,0.0003586019,0.0003308287,0.0001754103,0.0002354455,0.00005009017,0.00001718295],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.994337,"threshold_uncertainty_score":0.9999585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04000273258990221,"score_gpt":0.3393271517305479,"score_spread":0.2993244191406457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}