{"id":"W2058045419","doi":"10.3390/v6114505","title":"Cholesterol Balance in Prion Diseases and Alzheimer’s Disease","year":2014,"lang":"en","type":"review","venue":"Viruses","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Alberta Prion Research Institute","keywords":"Lipid raft; Cholesterol; Endosome; Cell biology; Biology; Glycoprotein; Gene isoform; Homeostasis; Biochemistry; Cell; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002821758,0.00067224,0.000952071,0.002091249,0.0003504062,0.0008132632,0.000520889,0.0009682024,0.002525923],"category_scores_gemma":[0.0003901616,0.0002064063,0.0003163262,0.00210885,0.0003515819,0.001122051,0.0006501662,0.001358025,0.001814171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006167761,"about_ca_system_score_gemma":0.0009490484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001116334,"about_ca_topic_score_gemma":0.001675816,"domain_scores_codex":[0.9998825,0.00001630492,0.00002028612,0.00001970823,0.00004818217,0.00001313795],"domain_scores_gemma":[0.9998845,0.00003699286,0.00001809492,0.000003809643,0.00003928777,0.00001720899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008421211,0.00006326232,0.000252431,0.01378332,0.00007195869,0.0003651246,0.00008572879,0.0002930212,0.0033065,0.004026756,0.02930804,0.9483596],"study_design_scores_gemma":[0.00001026941,0.00006608949,0.001047874,0.002320135,0.00008091425,0.001855187,0.00005130402,0.00006253881,0.0006311291,0.002378172,0.9914787,0.00001764964],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001343355,0.998517,0.00009428753,0.0001651796,0.0001488173,0.000002842478,0.00001431254,0.000007611532,0.0009155472],"genre_scores_gemma":[0.0008209887,0.9981748,0.0001415257,0.000102772,0.0001257713,0.000004341628,0.00002887932,0.000001329241,0.00059963],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002525923,"threshold_uncertainty_score":0.008450091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04000273258990221,"score_gpt":0.3393271517305479,"score_spread":0.2993244191406457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}