{"id":"W2058047561","doi":"10.1016/j.yexcr.2007.03.023","title":"Phenomics and lamins: From disease to therapy","year":2007,"lang":"en","type":"review","venue":"Experimental Cell Research","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"National Cancer Institute; National Institutes of Health; Health Canada; Canada Research Chairs; Heart and Stroke Foundation of Canada; Ontario Genomics Institute; Canadian Institutes of Health Research; Genome Canada","keywords":"LMNA; Biology; Lipodystrophy; Phenomics; Phenotype; Bioinformatics; Disease; Genetics; Computational biology; Gene; Genomics; Pathology; Medicine; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001545718,0.001315882,0.001953844,0.002186399,0.00041784,0.001589027,0.001925651,0.002707045,0.002852568],"category_scores_gemma":[0.001483179,0.0004110781,0.0004603663,0.002464334,0.001948485,0.002131422,0.0009556891,0.003405023,0.002673562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00135692,"about_ca_system_score_gemma":0.001258758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009874753,"about_ca_topic_score_gemma":0.001953949,"domain_scores_codex":[0.9996797,0.00006949612,0.00003500892,0.00004645892,0.0001402302,0.0000291056],"domain_scores_gemma":[0.9992587,0.0004156333,0.000052313,0.00003683703,0.0001770413,0.00005951432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001517631,0.0001144543,0.0001719639,0.007009378,0.00008791775,0.0004542401,0.0000549372,0.0007274052,0.003957557,0.01764635,0.09751271,0.8721113],"study_design_scores_gemma":[0.00002778912,0.00003608874,0.0002534118,0.0008040712,0.00003894584,0.001511273,0.00003373591,0.0001056951,0.0008241918,0.006228441,0.9901212,0.0000151346],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007563537,0.9963166,0.0006914926,0.00105735,0.0007519834,0.000005313624,0.00001402646,0.0000162813,0.0010712],"genre_scores_gemma":[0.0005208191,0.9964966,0.0006407635,0.0006525334,0.0005830692,0.00001209169,0.00002437475,0.000003329542,0.00106646],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002852568,"threshold_uncertainty_score":0.009845138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1604735780728058,"score_gpt":0.4624361600784771,"score_spread":0.3019625820056713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}