{"id":"W2058106189","doi":"10.1111/j.1471-4159.2004.02489.x","title":"Shift in the localization of sites of hydrogen peroxide production in brain mitochondria by mitochondrial stress","year":2004,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Antimycin A; Rotenone; Mitochondrion; Respiratory chain; Biochemistry; Succinate dehydrogenase; Substrate (aquarium); Mitochondrial respiratory chain; Biology; NAD+ kinase; Coenzyme Q – cytochrome c reductase; Chemistry; Biophysics; Cytochrome c; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000218986,0.0004349113,0.0003418275,0.0002027243,0.0001547737,0.0003428318,0.0001990696,0.0003711945,0.001069598],"category_scores_gemma":[0.0001517603,0.0001765504,0.000245246,0.0001322995,0.0003292167,0.0004676435,0.0002766984,0.0005857621,0.0002711275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001811937,"about_ca_system_score_gemma":0.0001097786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003218895,"about_ca_topic_score_gemma":0.0004483998,"domain_scores_codex":[0.9998804,0.00001988749,0.000009871588,0.00003815498,0.00002112043,0.00003049675],"domain_scores_gemma":[0.9998655,0.00001837183,0.00004663715,0.00001316807,0.00003169453,0.00002456363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001867746,0.00001032459,0.0003752199,0.00004789373,0.000008602914,0.00007068454,0.0000442861,0.00001587982,0.9982466,0.00006041173,0.00001335849,0.0009200066],"study_design_scores_gemma":[0.00002418356,0.000751314,0.02186898,0.00001769648,0.00004792347,0.0004792482,0.0001449697,0.0003830678,0.9751127,0.0002340088,0.0009270121,0.000008945008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856007,0.007590613,0.005458793,0.0001491082,0.00004516902,0.00003429233,0.0001838607,0.00007950563,0.0008579128],"genre_scores_gemma":[0.9939925,0.002308063,0.002753976,0.00005486479,0.00002493386,0.0000393782,0.0001744032,0.00001137053,0.0006405528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001069598,"threshold_uncertainty_score":0.003578186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00878117688159393,"score_gpt":0.2410218697241628,"score_spread":0.2322406928425688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}