{"id":"W2058130691","doi":"10.1074/jbc.m411522200","title":"Dominant-negative Retinoic Acid Receptors Elicit Epidermal Defects through a Non-canonical Pathway","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Retinoic acid; Receptor; Chemistry; Non canonical; Cell biology; Biology; Psychology; Internal medicine; Biochemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000129297,0.0004416693,0.0001684239,0.0002600032,0.0001082574,0.0002977665,0.0001589611,0.0002442065,0.001552841],"category_scores_gemma":[0.0001188844,0.0001964095,0.0001893865,0.0001328587,0.0002448651,0.0001826292,0.0002853704,0.0004548897,0.0006580847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000219413,"about_ca_system_score_gemma":0.0002408006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003363435,"about_ca_topic_score_gemma":0.0009215596,"domain_scores_codex":[0.9998053,0.00004248057,0.00002280053,0.00002459971,0.00006565379,0.00003929313],"domain_scores_gemma":[0.9998005,0.00003654835,0.00005290378,0.00004017257,0.00001906501,0.00005079911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003155289,0.000005806059,0.0001105344,0.00001176536,0.000001570526,0.00006715664,0.000005040275,0.00001783827,0.9992713,0.00007427185,0.00001022833,0.0003928675],"study_design_scores_gemma":[0.00001224003,0.0001457925,0.003687589,0.000003792736,0.00001166798,0.0009845661,0.00002920201,0.0003003387,0.9933105,0.00007897187,0.001432731,0.000002736084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939614,0.000780011,0.002225257,0.00006369279,0.0000119214,0.00001715351,0.0002555618,0.0001256119,0.002559396],"genre_scores_gemma":[0.9917373,0.0009883074,0.001978091,0.00003564093,0.000003974082,0.00001654791,0.0002407963,0.00002438361,0.004975008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001552841,"threshold_uncertainty_score":0.005194783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431182963705218,"score_gpt":0.2530841194119496,"score_spread":0.2387722897748975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}