{"id":"W2058131659","doi":"10.1007/s11888-013-0183-4","title":"How Do We Make Choices in Salvage Therapy: Panitumumab, Cetuximab, or Regorafenib?","year":2013,"lang":"en","type":"article","venue":"Current Colorectal Cancer Reports","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Panitumumab; Cetuximab; Medicine; KRAS; Regorafenib; Colorectal cancer; Oncology; Internal medicine; Epidermal growth factor receptor; EGFR inhibitors; Monoclonal antibody; Cancer; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001621204,0.0005215828,0.0009102682,0.0002420433,0.0001636096,0.0001963934,0.000123827,0.0001350638,0.001032057],"category_scores_gemma":[0.0001164515,0.0003484265,0.000235831,0.0006501769,0.0001807956,0.0002877134,0.0001238641,0.0004294323,0.00001931601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007087552,"about_ca_system_score_gemma":0.0004617809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000919259,"about_ca_topic_score_gemma":0.002210124,"domain_scores_codex":[0.9970918,0.00006129291,0.0006238633,0.0008903234,0.0006219691,0.0007106946],"domain_scores_gemma":[0.9985483,0.00008301556,0.0003964379,0.0004389676,0.0002756638,0.0002576428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001424744,0.0009584345,0.3371171,0.0002611114,0.0002980182,0.001237277,0.001203976,0.000003002199,0.001616523,0.00001883598,0.006943998,0.648917],"study_design_scores_gemma":[0.005122637,0.001945163,0.5908991,0.001042239,0.0001794747,0.0005761929,0.000708094,0.00005502157,0.003570674,0.0004508884,0.3946269,0.0008235917],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.905479,0.08412903,0.000002664594,0.00326723,0.002156203,0.00231754,0.00001926244,0.0001668325,0.002462249],"genre_scores_gemma":[0.970486,0.02353121,0.0000486602,0.0001149463,0.0005423335,0.002824065,0.00002354421,0.00006396446,0.002365289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6480933,"threshold_uncertainty_score":0.9998968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04351257910192568,"score_gpt":0.3259857666039023,"score_spread":0.2824731875019766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}