{"id":"W2058141808","doi":"10.1002/cncr.11287","title":"Targeted therapy and pharmacogenomic programs","year":2003,"lang":"en","type":"review","venue":"Cancer","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Response Biomedical (Canada)","funders":"","keywords":"Medicine; Pharmacogenomics; Oncology; Profiling (computer programming); Clinical trial; Gene expression profiling; Pharmacogenetics; Internal medicine; Bioinformatics; Toxicity; Pharmacology; Gene expression; Gene; Biology; Genetics; Computer science; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006397905,0.0002983627,0.0004959025,0.00003136304,0.00004680522,0.00003892534,0.0001448881,0.0002355606,0.00006885337],"category_scores_gemma":[0.000007302509,0.0002557987,0.0001872725,0.00007023162,0.00006576592,8.917226e-7,0.00005804323,0.0001167517,0.000009159269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004353392,"about_ca_system_score_gemma":0.00040429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001761192,"about_ca_topic_score_gemma":0.00001000765,"domain_scores_codex":[0.9990206,0.0000399462,0.0002155657,0.0004328773,0.00005266488,0.0002383281],"domain_scores_gemma":[0.9994605,0.00000873882,0.000132762,0.0002580084,0.00003630374,0.0001037399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007222296,0.0000192212,0.00001543393,0.0006388919,0.0001792944,0.0000020255,0.000005589819,4.115865e-7,0.0002019028,0.00001322458,0.004195182,0.9947216],"study_design_scores_gemma":[0.000293711,0.00007249397,0.000001638164,0.0003154131,0.0001512909,0.00001346698,0.000001835145,5.003887e-7,0.0001867201,0.00000741209,0.9986364,0.0003190972],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000368873,0.9980164,0.000009321081,0.000007637301,0.0005159501,0.0006007513,0.0001371819,0.000007642157,0.0003362327],"genre_scores_gemma":[0.00002577988,0.997471,0.00009428288,0.0002792168,0.0006017867,0.0004235457,0.000334723,0.00007357114,0.0006961404],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9944412,"threshold_uncertainty_score":0.9999894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05540167334482708,"score_gpt":0.3455721661810224,"score_spread":0.2901704928361953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}