{"id":"W2058186492","doi":"10.1016/j.joca.2013.02.360","title":"Altered cartilage phenotype in mice lacking Sirt 1 gene","year":2013,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Cartilage; Aggrecan; Osteoarthritis; Chondrocyte; Apoptosis; Mutant; Type II collagen; Cell biology; Biology; Molecular biology; Endocrinology; Pathology; Medicine; Gene; Anatomy; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003974915,0.001927418,0.0009779582,0.002945177,0.0006247298,0.0008289313,0.001030139,0.002324128,0.01241267],"category_scores_gemma":[0.0003441924,0.001045599,0.001227049,0.0008072724,0.002041708,0.0006611169,0.0007355146,0.002795513,0.00200713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006406063,"about_ca_system_score_gemma":0.0006841965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001427713,"about_ca_topic_score_gemma":0.00239675,"domain_scores_codex":[0.9992012,0.00007758517,0.0001000204,0.0002469549,0.0002349761,0.0001392014],"domain_scores_gemma":[0.9988509,0.00008919575,0.0005283467,0.00006894874,0.00005905771,0.0004035535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004718223,0.00009908313,0.0001588182,0.00005791899,0.00002554457,0.0003869178,0.00002951109,0.00008559594,0.9975262,0.0002745936,0.0001233713,0.0007606236],"study_design_scores_gemma":[0.000818004,0.001507209,0.01555287,0.00008377766,0.0003843671,0.005347632,0.0003526141,0.001636925,0.9658397,0.0008255951,0.007554858,0.00009645407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978784,0.002639729,0.00804092,0.001171394,0.0006118735,0.00008802609,0.004286954,0.001065734,0.003311387],"genre_scores_gemma":[0.9563783,0.002305542,0.007294076,0.0006372547,0.0001462162,0.0002250619,0.00241798,0.0007034516,0.02989218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01241267,"threshold_uncertainty_score":0.04152453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116979188203442,"score_gpt":0.2273052884676106,"score_spread":0.2161354965855761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}