{"id":"W2058262378","doi":"10.1038/nature03041","title":"The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II","year":2004,"lang":"en","type":"article","venue":"Nature","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":560,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Polyadenylation; RNA polymerase II; Exonuclease; Termination factor; Transcription (linguistics); Antitermination; CTD; RNA; Cell biology; Cleavage and polyadenylation specificity factor; Chemistry; Molecular biology; Messenger RNA; Transcription factor II D; Biology; Gene; Polymerase; Genetics; Promoter; Gene expression; RNA polymerase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001062083,0.00007955178,0.00004462257,0.00001565866,0.0002790134,0.00003961312,0.0001368949,0.000376339,0.000006573669],"category_scores_gemma":[0.00006844903,0.00005564695,0.00004894611,0.00006006092,0.00004493622,0.000005602597,0.00002481174,0.0004283929,0.000005040165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001567997,"about_ca_system_score_gemma":0.00004747848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001763928,"about_ca_topic_score_gemma":0.00002758959,"domain_scores_codex":[0.9994051,0.00002546965,0.00007490021,0.0001651705,0.0001481694,0.0001811259],"domain_scores_gemma":[0.9996881,0.000002918184,0.00002464797,0.0001681051,0.0000493876,0.00006682092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005948987,0.00003886889,0.00001090916,0.000004700217,0.000009817492,0.000002703517,0.00002719494,0.00000200979,0.9795837,0.00008316016,0.004898353,0.01527905],"study_design_scores_gemma":[0.0005170495,0.0001765847,0.0002354046,0.00001014537,0.00000457802,0.000008169565,0.00003050195,0.00002463381,0.9693642,0.0001177134,0.02943145,0.00007956721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923455,0.003540352,0.00009897682,0.003281403,0.00008477208,0.0001494049,0.00002352704,0.00001043478,0.0004656931],"genre_scores_gemma":[0.9960808,0.0001769004,0.00004814231,0.0004262283,0.0001489078,0.00001164137,0.000114723,0.00001145926,0.002981232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02453309,"threshold_uncertainty_score":0.2902671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004103352674095432,"score_gpt":0.2477239326624855,"score_spread":0.2436205799883901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}