{"id":"W2058262378","doi":"10.1038/nature03041","title":"The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II","year":2004,"lang":"en","type":"article","venue":"Nature","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":560,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Polyadenylation; RNA polymerase II; Exonuclease; Termination factor; Transcription (linguistics); Antitermination; CTD; RNA; Cell biology; Cleavage and polyadenylation specificity factor; Chemistry; Molecular biology; Messenger RNA; Transcription factor II D; Biology; Gene; Polymerase; Genetics; Promoter; Gene expression; RNA polymerase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007270246,0.0007313748,0.0004458829,0.000394849,0.0003081274,0.0008808068,0.0003298133,0.0003770534,0.001257771],"category_scores_gemma":[0.0005156519,0.0004335684,0.0004133567,0.0002084919,0.0003983129,0.0003811006,0.0004105148,0.0007077664,0.001228693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005890491,"about_ca_system_score_gemma":0.0003473201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005594477,"about_ca_topic_score_gemma":0.001094623,"domain_scores_codex":[0.9996806,0.00006787788,0.00002528408,0.00006703439,0.00008663915,0.00007257939],"domain_scores_gemma":[0.9994121,0.0002341617,0.0001006357,0.00007631092,0.00008406362,0.00009265413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002299991,0.00001310937,0.0003732563,0.00003776563,0.000004897339,0.00009047821,0.0000224014,0.000181185,0.9962701,0.0005112924,0.00008649883,0.002178974],"study_design_scores_gemma":[0.00001023685,0.00006388753,0.000759405,0.000005150319,0.000006258665,0.0001277314,0.00001461026,0.0008282205,0.996872,0.0001473759,0.001161225,0.000003878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738695,0.005955813,0.01484734,0.0002871537,0.0002097566,0.0000250863,0.0001697242,0.0006612182,0.003974349],"genre_scores_gemma":[0.9888439,0.001281706,0.005220408,0.00007726178,0.00007221293,0.00001315704,0.0004484239,0.0001707204,0.00387219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001257771,"threshold_uncertainty_score":0.004273832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004103352674095432,"score_gpt":0.2477239326624855,"score_spread":0.2436205799883901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}