{"id":"W2058272767","doi":"10.1152/ajpendo.00604.2007","title":"In vivo regulation of phenylalanine hydroxylation to tyrosine, studied using enrichment in apoB-100","year":2007,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Phenylalanine; Tyrosine; Hydroxylation; Amino acid; Chemistry; Apolipoprotein B; Methionine; Biochemistry; In vivo; Chromatography; Biology; Enzyme; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001236397,0.0002055101,0.0002091559,0.0001533622,0.0001325178,0.0002235608,0.000126192,0.0002656073,0.0007960245],"category_scores_gemma":[0.0001432369,0.0001675024,0.0001197122,0.0001305357,0.0002811369,0.0001808264,0.0001116656,0.0003760855,0.0001809706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004207278,"about_ca_system_score_gemma":0.0001470971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001785308,"about_ca_topic_score_gemma":0.002720969,"domain_scores_codex":[0.9999326,0.00001295804,0.000002643652,0.00003064385,0.00001108348,0.000009983331],"domain_scores_gemma":[0.999905,0.00002432379,0.00002250892,0.00001112013,0.00001102198,0.00002607261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008665202,0.00002946239,0.001164878,0.00001055561,0.000005916059,0.00002004846,0.00001450955,0.00002803685,0.9970783,0.00002168944,0.0000121751,0.0007478488],"study_design_scores_gemma":[0.00005248099,0.001441941,0.05228326,0.000004140341,0.00003853039,0.0002439198,0.00005123106,0.001513531,0.9430622,0.00007897679,0.00122292,0.000006794107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976283,0.0007188864,0.001164448,0.00002574765,0.000006451926,0.000008698575,0.0001448187,0.00001317672,0.0002895445],"genre_scores_gemma":[0.9940528,0.0006555772,0.001499525,0.00004545604,0.000007689237,0.00003810736,0.0003193208,0.00002391658,0.003357552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001785308,"threshold_uncertainty_score":0.003549874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009296066417379598,"score_gpt":0.2758200045248876,"score_spread":0.266523938107508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}