{"id":"W2058277629","doi":"10.1139/y11-028","title":"The effect of<i>N</i>-acetylcysteine on the antitumor activity of ifosfamide","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Chemotherapy-induced organ toxicity mitigation","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children; Children’s Health Research Institute; Western University","funders":"","keywords":"Ifosfamide; Acetylcysteine; Pharmacology; Chemistry; Medicine; Chemotherapy; Internal medicine; Biochemistry; Antioxidant; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001300107,0.0002124546,0.0002757522,0.0001316954,0.0001037069,0.0001393866,0.00020181,0.0002175787,0.0009431595],"category_scores_gemma":[0.0001653952,0.00008354566,0.000175564,0.0001408819,0.0001618563,0.0001702295,0.00009914015,0.0003277402,0.0001428867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001775276,"about_ca_system_score_gemma":0.0002590115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00143348,"about_ca_topic_score_gemma":0.001925394,"domain_scores_codex":[0.9999043,0.00003012972,0.000009976404,0.00001294492,0.00001831974,0.00002423015],"domain_scores_gemma":[0.9998854,0.00002768126,0.00002256406,0.00001215586,0.00001911174,0.00003311781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001993754,0.0001497147,0.0005501573,0.00006680228,0.00002200913,0.00006428106,0.00002265391,0.0001239804,0.9928342,0.00007880771,0.00007518716,0.004018347],"study_design_scores_gemma":[0.00003139114,0.002033716,0.003810031,0.000005859301,0.00002542074,0.0001401598,0.00001577862,0.0003764318,0.9923235,0.00001412719,0.00121998,0.000003573507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964867,0.001801401,0.000281494,0.00004893303,0.00002372343,0.00001751207,0.00007667334,0.00002478238,0.001238826],"genre_scores_gemma":[0.9974704,0.000864274,0.0007132535,0.00003492705,0.000008599726,0.00001190052,0.0001732756,0.000007368233,0.0007161144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00143348,"threshold_uncertainty_score":0.003155172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01814317258821934,"score_gpt":0.2647663037298042,"score_spread":0.2466231311415849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}