{"id":"W2058283232","doi":"10.1158/0008-5472.can-06-3399","title":"Attenuation of the Glucocorticoid Response during Ad5IL-12 Adenovirus Vector Treatment Enhances Natural Killer Cell–Mediated Killing of MHC Class I–Negative LNCaP Prostate Tumors","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"NKG2D; Cancer research; LNCaP; MHC class I; Biology; NK-92; Interleukin 12; Immunology; Natural killer cell; Nod; Immunotherapy; Major histocompatibility complex; Immune system; Cancer cell; Interleukin 21; Cancer; Cytotoxic T cell; T cell; Endocrinology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001789048,0.0004847712,0.0003658485,0.0002491608,0.0001238089,0.0003303168,0.0002153531,0.0002193107,0.001320642],"category_scores_gemma":[0.0001082492,0.0001348118,0.0002900333,0.0001611646,0.0002567135,0.0001732092,0.0001577317,0.001009079,0.0004186484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003264096,"about_ca_system_score_gemma":0.0002954609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001082543,"about_ca_topic_score_gemma":0.001737514,"domain_scores_codex":[0.9997506,0.00004039503,0.00002533499,0.00004922002,0.00005530352,0.0000791438],"domain_scores_gemma":[0.9998537,0.00002369485,0.00002898241,0.00002301315,0.00001246293,0.00005808869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001428618,0.00006988106,0.00007911248,0.00002519579,0.000003079949,0.00001454878,0.00001771648,0.00003947851,0.9987679,0.00003483182,0.00002655912,0.0007788038],"study_design_scores_gemma":[0.00002112078,0.0007861038,0.00159101,0.000003531826,0.00001150773,0.00005895467,0.00001748256,0.0004401931,0.9957691,0.0000105563,0.001286474,0.000003863918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956949,0.001103498,0.001408193,0.00009046988,0.00009707751,0.00005492207,0.0004072108,0.0001638635,0.0009797901],"genre_scores_gemma":[0.9938229,0.0006203844,0.001794068,0.00003804754,0.00002056563,0.00006492784,0.0005738094,0.00002381756,0.003041279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001320642,"threshold_uncertainty_score":0.004417956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02856687315823789,"score_gpt":0.326863755537234,"score_spread":0.2982968823789961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}