{"id":"W2058299529","doi":"10.2217/nnm.11.23","title":"Self-Assembled Multifunctional Nanoplexes for Gene Inhibitory Therapy","year":2011,"lang":"en","type":"article","venue":"Nanomedicine","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Inhibitory postsynaptic potential; Genetic enhancement; Gene; Biology; Genetics; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001397447,0.000136408,0.0001351337,0.00005061705,0.00006510756,0.000004732973,0.0001312119,0.0001258175,0.00008909513],"category_scores_gemma":[0.00002101686,0.0001092119,0.00008574465,0.00004877616,0.00002517105,0.000003839519,0.00002903694,0.00004419214,0.00002015405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001126978,"about_ca_system_score_gemma":0.00007616643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001807854,"about_ca_topic_score_gemma":0.000008550644,"domain_scores_codex":[0.9992297,0.00001702958,0.0001813592,0.0002775226,0.00009755362,0.0001968079],"domain_scores_gemma":[0.9995031,0.00001015061,0.00006018085,0.0002169899,0.0001408221,0.00006879655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003582362,0.0001299544,0.001670853,0.00001052056,0.00008771364,0.000001662022,0.0001509162,4.532952e-7,0.9882007,0.00002069832,0.005977111,0.003391163],"study_design_scores_gemma":[0.001733021,0.00140007,0.003636706,0.000009408569,0.00001606603,0.00001163287,0.00007186594,0.00002553243,0.9128975,0.00005479304,0.0799963,0.0001471473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940264,0.001905721,0.001690909,0.00006912473,0.0006491185,0.0002790138,0.000009382809,0.00002727038,0.001343119],"genre_scores_gemma":[0.992721,0.0007238173,0.003552938,0.0007913475,0.0009567862,0.00009900439,0.00010318,0.00002178954,0.001030101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07530326,"threshold_uncertainty_score":0.4453531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02957997895267218,"score_gpt":0.2482419463050337,"score_spread":0.2186619673523615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}