{"id":"W2058299529","doi":"10.2217/nnm.11.23","title":"Self-Assembled Multifunctional Nanoplexes for Gene Inhibitory Therapy","year":2011,"lang":"en","type":"article","venue":"Nanomedicine","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Inhibitory postsynaptic potential; Genetic enhancement; Gene; Biology; Genetics; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001938555,0.0002552095,0.0002307429,0.0001825018,0.0001220977,0.0002872611,0.0002477615,0.0004617577,0.0007378363],"category_scores_gemma":[0.0002110468,0.000132083,0.0001424022,0.00009978539,0.0001919659,0.0003017788,0.0001905746,0.0002672822,0.0003644094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004958284,"about_ca_system_score_gemma":0.0001970897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002449336,"about_ca_topic_score_gemma":0.0004465709,"domain_scores_codex":[0.9998889,0.00001512777,0.00001136649,0.00003582507,0.00003294444,0.00001594252],"domain_scores_gemma":[0.9998922,0.00002137072,0.00003114909,0.000007842074,0.00002320631,0.00002421211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003552288,0.00001923865,0.00005796885,0.00004200858,0.000005638682,0.00003429069,0.00001218939,0.0002803387,0.9969673,0.0002074262,0.00005933936,0.002278776],"study_design_scores_gemma":[0.0000185266,0.0001331067,0.0002416168,0.000003494239,0.0000134459,0.0001186058,0.000006675289,0.002740678,0.9940032,0.00006321848,0.002652176,0.000005329917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9312555,0.00422661,0.06005673,0.0002981686,0.00009901435,0.0002861403,0.0003075528,0.0005217115,0.002948569],"genre_scores_gemma":[0.9653457,0.0008549115,0.02990605,0.0001631168,0.00001737964,0.0001142706,0.0002520918,0.00004038403,0.003306132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007378363,"threshold_uncertainty_score":0.003597438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02957997895267218,"score_gpt":0.2482419463050337,"score_spread":0.2186619673523615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}