{"id":"W2058326536","doi":"10.1002/ange.200890300","title":"Titelbild: Solid‐Supported Synthesis and Biological Evaluation of the Lantibiotic Peptide Bis(desmethyl) Lacticin 3147 A2 (Angew. Chem. 49/2008)","year":2008,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Lantibiotics; Chemistry; Peptide; Stereochemistry; Biochemistry; Bacteriocin; Organic chemistry; Antimicrobial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000254279,0.0004710588,0.0002169042,0.0003429478,0.0001837162,0.0002903656,0.0003724152,0.0003703172,0.003969043],"category_scores_gemma":[0.0001549958,0.0001477264,0.0002396677,0.0002103316,0.0001792729,0.0002947207,0.0002745536,0.0003620285,0.001956278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002026338,"about_ca_system_score_gemma":0.0001729646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007082162,"about_ca_topic_score_gemma":0.0006785602,"domain_scores_codex":[0.9998235,0.00002863935,0.00001038923,0.00002775371,0.00008759573,0.00002214378],"domain_scores_gemma":[0.9999454,0.00001171328,0.00001211776,0.000005434614,0.00001259716,0.00001263222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001120656,0.00002427125,0.00002168926,0.00004567168,0.000002852486,0.00006048657,0.00001530828,0.0001547326,0.9967998,0.00009991323,0.0001704529,0.002492727],"study_design_scores_gemma":[0.00004262349,0.000361248,0.000314663,0.000005763255,0.000007313316,0.0001026944,0.00001344186,0.000935917,0.9925564,0.00008086835,0.005570684,0.000008390934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9244849,0.01071318,0.0374666,0.0008254306,0.0006315309,0.0003479734,0.002171989,0.00103981,0.02231864],"genre_scores_gemma":[0.9171193,0.004760457,0.03649501,0.0001243683,0.00007791591,0.0001202778,0.003200023,0.0001628342,0.03793975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003969043,"threshold_uncertainty_score":0.01327777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03777807949113497,"score_gpt":0.2779578429600336,"score_spread":0.2401797634688986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}