{"id":"W2058342356","doi":"10.1002/gene.1016","title":"An X‐linked GFP transgene reveals unexpected paternal X‐chromosome activity in trophoblastic giant cells of the mouse placenta","year":2001,"lang":"en","type":"letter","venue":"genesis","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Medical Research Council; National Health and Medical Research Council","keywords":"Transgene; Biology; Green fluorescent protein; X-inactivation; Embryonic stem cell; Molecular biology; Genetically modified mouse; Somatic cell; Embryo; Chromosome; Cell sorting; X chromosome; Placenta; Reporter gene; Gene; Genetics; Cell biology; Flow cytometry; Gene expression; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001374497,0.0004260042,0.0005444982,0.00008236646,0.00008029518,0.00003329508,0.0007705124,0.0008816125,0.0002073004],"category_scores_gemma":[0.00002412154,0.0003282523,0.0003439663,0.0001428618,0.000212605,0.000007090239,0.0001081573,0.0004784169,0.00001008925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003806961,"about_ca_system_score_gemma":0.0001282918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002180913,"about_ca_topic_score_gemma":0.0001663733,"domain_scores_codex":[0.9974776,0.0003664523,0.0006348912,0.0006512667,0.0003948417,0.0004749399],"domain_scores_gemma":[0.9985881,0.0000399518,0.0003494441,0.0008117699,0.0001156417,0.0000951012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001464043,0.0002556655,0.0009451473,0.0001588075,0.0000756824,0.00005126565,0.0000830509,0.0001140397,0.9866123,5.669967e-7,0.0107281,0.0008289402],"study_design_scores_gemma":[0.001420268,0.0008619527,0.02120508,0.0001024651,0.0001227086,0.00003128026,0.0001225433,0.00008609971,0.9555947,0.00005141736,0.01970489,0.0006965785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917025,0.0002491339,0.00008892696,0.006837196,0.0003046546,0.0003625935,0.0003342372,0.00001524989,0.0001055222],"genre_scores_gemma":[0.9750438,0.0006922446,0.0001215351,0.01794047,0.001171059,0.00004635762,0.0002615406,0.0000677897,0.004655154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03101761,"threshold_uncertainty_score":0.999917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01335627539517095,"score_gpt":0.2420060999545389,"score_spread":0.2286498245593679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}