{"id":"W2058451295","doi":"10.7326/m13-1921","title":"<i>N</i>-of-1 (Single-Patient) Trials for Statin-Related Myalgia","year":2014,"lang":"en","type":"article","venue":"Annals of Internal Medicine","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":134,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"myalgia; Medicine; Statin; Placebo; Discontinuation; Internal medicine; Visual analogue scale; Physical therapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00335831,0.001155423,0.002778362,0.0004187057,0.0006215376,0.0008893035,0.0008166968,0.002444451,0.01165277],"category_scores_gemma":[0.003603827,0.0004781217,0.001894842,0.0003005026,0.0006411365,0.0009770776,0.0004093746,0.002074355,0.001016634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004863439,"about_ca_system_score_gemma":0.0008190142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003117786,"about_ca_topic_score_gemma":0.00124196,"domain_scores_codex":[0.997891,0.001487381,0.0001856559,0.0001893975,0.0001065076,0.0001400906],"domain_scores_gemma":[0.9980707,0.0006845669,0.0006582518,0.000152343,0.0001029393,0.0003313321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9489971,0.004745139,0.001091202,0.002569541,0.001865975,0.00005359691,0.00006238494,0.0001703652,0.002623192,0.0002263204,0.002544263,0.0350508],"study_design_scores_gemma":[0.9525927,0.04238832,0.002020119,0.0001929093,0.0006025687,0.0000519449,0.00001492376,0.0001620856,0.0002402936,0.0001881672,0.001534871,0.00001113389],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8925946,0.04420574,0.002761434,0.006053684,0.002607536,0.03300637,0.004030347,0.0003761857,0.01436396],"genre_scores_gemma":[0.9461173,0.007666978,0.005096171,0.00428384,0.001818902,0.02926687,0.001453385,0.00004432733,0.004252266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01165277,"threshold_uncertainty_score":0.03898239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0965059449467259,"score_gpt":0.3663289738589935,"score_spread":0.2698230289122676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}