{"id":"W2058458460","doi":"10.1203/01.pdr.0000179408.74781.c9","title":"Lineage Development in a Patient without Goblet, Paneth, and Enteroendocrine Cells: A Clue for Intestinal Epithelial Differentiation","year":2005,"lang":"en","type":"article","venue":"Pediatric Research","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"University of Toronto; American Physicians Fellowship for Medicine in Israel","keywords":"Paneth cell; Enteroendocrine cell; Enterocyte; Biology; Cell biology; Lineage (genetic); Cellular differentiation; Goblet cell; Stem cell; Endocrine system; Small intestine; Genetics; Epithelium; Endocrinology; Hormone; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003685008,0.00124251,0.00103389,0.001900587,0.002037207,0.001128969,0.00117115,0.005112291,0.002780479],"category_scores_gemma":[0.003062887,0.000703441,0.0005423736,0.0008492242,0.001161336,0.00162135,0.0009672523,0.002796126,0.0006988884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008286159,"about_ca_system_score_gemma":0.0005678526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001745098,"about_ca_topic_score_gemma":0.00172212,"domain_scores_codex":[0.9995319,0.00006208831,0.00005594249,0.0001247273,0.00007088862,0.0001546128],"domain_scores_gemma":[0.9984637,0.0005940936,0.00009378229,0.0000842968,0.00008533383,0.0006787739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001594522,0.00003495203,0.01945395,0.00001896858,0.0000047715,0.9754776,0.0001858633,0.00007633993,0.002151618,0.0004171242,0.0002110847,0.001808187],"study_design_scores_gemma":[0.0000163115,0.0001437084,0.01166765,0.00001459006,0.00001358779,0.9856724,0.0001556684,0.0003171603,0.001130715,0.0002334589,0.0006228176,0.00001192749],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813299,0.001694949,0.001341464,0.004634589,0.0001436203,0.00008855991,0.0003152299,0.0001617867,0.01028989],"genre_scores_gemma":[0.9949338,0.0007436555,0.001558729,0.0009777998,0.0002711079,0.0000174585,0.0001486418,0.00004705582,0.001301785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005112291,"threshold_uncertainty_score":0.009301603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03027325249116306,"score_gpt":0.337845125609267,"score_spread":0.3075718731181039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}