{"id":"W2058458460","doi":"10.1203/01.pdr.0000179408.74781.c9","title":"Lineage Development in a Patient without Goblet, Paneth, and Enteroendocrine Cells: A Clue for Intestinal Epithelial Differentiation","year":2005,"lang":"en","type":"article","venue":"Pediatric Research","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"University of Toronto; American Physicians Fellowship for Medicine in Israel","keywords":"Paneth cell; Enteroendocrine cell; Enterocyte; Biology; Cell biology; Lineage (genetic); Cellular differentiation; Goblet cell; Stem cell; Endocrine system; Small intestine; Genetics; Epithelium; Endocrinology; Hormone; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005908572,0.0001137468,0.0001354306,0.0001877055,0.0001074251,0.00002639747,0.00009905739,0.00008473201,0.00000604685],"category_scores_gemma":[0.0001622433,0.00009467936,0.00002722167,0.0001393704,0.00003609783,0.00000463313,0.0001273828,0.0001891152,0.00001237852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005484643,"about_ca_system_score_gemma":0.0001857965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004204412,"about_ca_topic_score_gemma":0.0001270474,"domain_scores_codex":[0.9985136,0.0001623771,0.0003293726,0.0003406312,0.000230237,0.0004237257],"domain_scores_gemma":[0.9994529,0.00006626725,0.00006379052,0.0001253295,0.000172477,0.0001192107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002500222,0.002074441,0.6500228,0.001980783,0.00012631,0.00004917371,0.004121359,0.0004447054,0.2230812,0.000182774,0.007661281,0.107755],"study_design_scores_gemma":[0.01457483,0.007061702,0.1714362,0.0003135092,0.00007760245,0.0001679072,0.0009133538,0.00618592,0.5370225,0.0001384072,0.2606314,0.001476643],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966912,0.00100915,0.001138891,0.0001457286,0.00008525081,0.0007200731,0.00001243052,0.000006994206,0.0001902273],"genre_scores_gemma":[0.9955156,0.0009793787,0.002161045,0.00003044706,0.0005506404,0.0001719724,0.00007000883,0.00001704397,0.0005038728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4785866,"threshold_uncertainty_score":0.3860912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03027325249116306,"score_gpt":0.337845125609267,"score_spread":0.3075718731181039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}