{"id":"W2058517191","doi":"10.1242/jcs.076026","title":"Inducible nitric oxide synthase–nitric oxide signaling mediates the mitogenic activity of Rac1 during endochondral bone growth","year":2011,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Chondrocyte; RAC1; Biology; Nitric oxide synthase; Cell biology; Nitric oxide; Cyclin D1; Signal transduction; Endochondral ossification; Endocrinology; Cartilage; Cell cycle; Biochemistry; Cell; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001086209,0.000173745,0.000244517,0.0002626693,0.0002338271,0.00004061389,0.0009387769,0.00007867742,0.00003361407],"category_scores_gemma":[0.0008650208,0.0001240571,0.0002056828,0.0006868055,0.000473158,0.00005309936,0.0002077614,0.0002434286,0.000003854021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004067364,"about_ca_system_score_gemma":0.0005774303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003586919,"about_ca_topic_score_gemma":0.000001818738,"domain_scores_codex":[0.9980847,0.0001124503,0.000482,0.0002852743,0.0006389805,0.00039657],"domain_scores_gemma":[0.9981463,0.0001066833,0.0007892982,0.0003394184,0.0003991645,0.0002191667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001387893,0.0001826838,0.006042324,0.00003291272,0.00002378804,0.00002490694,0.00007447759,0.0001006848,0.9932532,0.000002923355,0.00003070451,0.00009261964],"study_design_scores_gemma":[0.0003857246,0.00009204642,0.04326359,0.00003866462,0.00006012469,0.00009607186,0.0001153085,0.00001612431,0.9556954,0.00007571818,0.00002155108,0.0001396666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973508,0.001861503,0.0003386501,0.0000152716,0.000112683,0.0000937345,0.000004287891,0.000005486464,0.000217645],"genre_scores_gemma":[0.9977211,0.0001301382,0.001882,0.00002816887,0.0001633567,0.000002982639,5.540686e-7,0.00001519897,0.00005651934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03755778,"threshold_uncertainty_score":0.5058901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01552098844395455,"score_gpt":0.2296610140485739,"score_spread":0.2141400256046193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}