{"id":"W2058578803","doi":"10.1016/j.jsbmb.2013.08.002","title":"Intravaginal prasterone (DHEA) provides local action without clinically significant changes in serum concentrations of estrogens or androgens","year":2013,"lang":"en","type":"article","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Menopause: Health Impacts and Treatments","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Theratechnologies (Canada)","funders":"Bayer","keywords":"Dehydroepiandrosterone; Endocrinology; Internal medicine; Testosterone (patch); Estrone; Androsterone; Androgen; Dehydroepiandrosterone sulfate; Estrogen; Medicine; Chemistry; Steroid; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001511993,0.0003270822,0.0004178158,0.0003675226,0.0001775507,0.0001643352,0.0002016693,0.0002607154,0.003625249],"category_scores_gemma":[0.0003295662,0.0001024809,0.0002446953,0.0002010249,0.0003423396,0.0002030115,0.0002208404,0.0004534973,0.0006614752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009872327,"about_ca_system_score_gemma":0.0002895473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003953831,"about_ca_topic_score_gemma":0.001012123,"domain_scores_codex":[0.9998897,0.00003452726,0.000007136921,0.00001730272,0.00002845728,0.00002274542],"domain_scores_gemma":[0.9998331,0.00006174648,0.00003477274,0.00001845365,0.000008490811,0.000043429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.009747379,0.001028056,0.003008092,0.0008994355,0.0001060916,0.0008594193,0.000138457,0.0003263808,0.8127277,0.0007800983,0.001056341,0.1693226],"study_design_scores_gemma":[0.003099603,0.05060781,0.07108822,0.0001537898,0.0003837683,0.01157467,0.0005990473,0.0009152959,0.8096459,0.0006723491,0.05118649,0.00007313661],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9706142,0.01621394,0.003483494,0.0003490132,0.000145018,0.00009124885,0.0004541852,0.0006213485,0.008027583],"genre_scores_gemma":[0.9905185,0.003004066,0.001707565,0.0001256837,0.0001034283,0.00002764951,0.0001706231,0.0000304169,0.004312096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003625249,"threshold_uncertainty_score":0.01212764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03335538707535215,"score_gpt":0.3476812222190709,"score_spread":0.3143258351437188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}