{"id":"W2058657462","doi":"10.1006/excr.2001.5412","title":"Retinoic Acid Inhibits Telomerase Activity and Downregulates Expression but Does Not Affect Splicing of hTERT: Correlation with Cell Growth Rate Inhibition in an in Vitro Cervical Carcinogenesis/Multidrug-Resistance Model","year":2002,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dr. H. Bliss Murphy Cancer Centre; Memorial University of Newfoundland","funders":"","keywords":"Telomerase; Telomerase reverse transcriptase; Biology; Carcinogenesis; Molecular biology; Retinoic acid; Cell culture; Cell growth; Cancer research; Cell; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004273423,0.0005930287,0.0008492266,0.0007865517,0.0002933599,0.0005041946,0.000490228,0.000493374,0.002224115],"category_scores_gemma":[0.0005273663,0.0004254038,0.0006112104,0.0005896695,0.0006128959,0.0004636224,0.0002717387,0.001207185,0.0006502464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00051281,"about_ca_system_score_gemma":0.0004380372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001839756,"about_ca_topic_score_gemma":0.00190452,"domain_scores_codex":[0.9995146,0.0001481075,0.00006957342,0.000067705,0.0001024287,0.00009750058],"domain_scores_gemma":[0.9985883,0.0005036659,0.0002653256,0.0004068952,0.00007398122,0.0001618357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005564299,0.000089211,0.0003331241,0.00001584659,0.00001028804,0.00006673852,0.00001800249,0.00007060618,0.998097,0.0001133045,0.00003105032,0.0005984573],"study_design_scores_gemma":[0.00001336113,0.0002664858,0.001192866,0.000001002451,0.00001543789,0.0001207772,0.00001217162,0.0002735669,0.997786,0.00002290159,0.0002926813,0.00000269237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928069,0.001831771,0.002820946,0.0001841375,0.00004391191,0.00003230465,0.0006469216,0.0001983544,0.001434725],"genre_scores_gemma":[0.9930719,0.001103407,0.001513655,0.00003599673,0.0000185488,0.00004548218,0.000899235,0.00007562705,0.003236147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002224115,"threshold_uncertainty_score":0.007440388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02058860604130686,"score_gpt":0.2827595451737884,"score_spread":0.2621709391324816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}