{"id":"W2058657462","doi":"10.1006/excr.2001.5412","title":"Retinoic Acid Inhibits Telomerase Activity and Downregulates Expression but Does Not Affect Splicing of hTERT: Correlation with Cell Growth Rate Inhibition in an in Vitro Cervical Carcinogenesis/Multidrug-Resistance Model","year":2002,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dr. H. Bliss Murphy Cancer Centre; Memorial University of Newfoundland","funders":"","keywords":"Telomerase; Telomerase reverse transcriptase; Biology; Carcinogenesis; Molecular biology; Retinoic acid; Cell culture; Cell growth; Cancer research; Cell; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005116419,0.0002297744,0.0002339565,0.0001909282,0.0001219086,0.0000412538,0.0001220446,0.0002167452,0.00001214413],"category_scores_gemma":[0.00002338492,0.0001858899,0.00003739857,0.0002320093,0.0002343453,0.00005222922,0.000177251,0.0002977436,0.000001563944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000997096,"about_ca_system_score_gemma":0.00005023594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007929775,"about_ca_topic_score_gemma":0.00006876275,"domain_scores_codex":[0.9978506,0.0004434488,0.0002497438,0.0006601182,0.0003844645,0.0004116387],"domain_scores_gemma":[0.999338,0.00005589805,0.00009852387,0.0002894065,0.00009743966,0.0001207623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001731882,0.0004438701,0.003255785,0.0002397638,0.000002345204,0.00001989774,0.0007804084,0.0003904859,0.9930421,0.00000237036,0.000008647347,0.00008252128],"study_design_scores_gemma":[0.001677136,0.0003259811,0.001014427,0.0001060779,0.000003070297,0.000003066325,0.0005460268,0.009846879,0.9862337,0.00001185846,0.00000116485,0.0002306133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975851,0.001251208,0.0001373616,0.00003152466,0.00001553347,0.0004423247,0.00001594784,0.000008720827,0.0005123393],"genre_scores_gemma":[0.9987329,0.0002150919,0.0005266806,0.00001495603,0.00003767517,0.00008990768,0.00005787015,0.00003604951,0.0002888402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009456393,"threshold_uncertainty_score":0.7580371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02058860604130686,"score_gpt":0.2827595451737884,"score_spread":0.2621709391324816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}