{"id":"W2058680739","doi":"10.1016/j.virusres.2013.06.008","title":"Evidence suggesting that HCV p7 protects E2 glycoprotein from premature degradation during virus production","year":2013,"lang":"en","type":"article","venue":"Virus Research","topic":"Hepatitis C virus research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Center for Virus Research, University of California, Irvine; Faculty of Medicine, Memorial University of Newfoundland; Canadian Institutes of Health Research; Toray Industries; University of Glasgow","keywords":"Biology; Endoplasmic reticulum; Cell biology; Hepatitis C virus; NS3; Glycoprotein; Viral replication; Mutant; Virus; Infectivity; NS5A; Transmembrane protein; Virology; Cytoplasm; Biochemistry; Gene; Hepacivirus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.002593714,0.0003464324,0.0004724938,0.0008531004,0.0006464601,0.0004237547,0.0005393252,0.0003928215,0.001366913],"category_scores_gemma":[0.01307597,0.000302751,0.0001137275,0.001726652,0.0003451618,0.00137356,0.0004859766,0.002536735,0.002682875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008412008,"about_ca_system_score_gemma":0.0005959092,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03236625,"about_ca_topic_score_gemma":0.002535014,"domain_scores_codex":[0.9920543,0.00108923,0.000529323,0.001232722,0.003666673,0.001427697],"domain_scores_gemma":[0.9956818,0.0005845258,0.0001396996,0.001376778,0.001636421,0.0005808398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005410722,0.0001776911,0.01486555,0.0005082676,0.00005944938,0.0001250761,0.0004943649,0.00001008618,0.9097859,0.000009539864,0.002790784,0.0706322],"study_design_scores_gemma":[0.0007509852,0.0003856363,0.1082022,0.002568476,0.00001581067,0.00002817336,0.0001620541,0.0008204535,0.8833719,0.0003367494,0.003048614,0.0003089616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846463,0.001926275,0.00006465743,0.004254081,0.0001624123,0.007375909,0.00001530904,0.0004386604,0.001116398],"genre_scores_gemma":[0.9884267,0.001198115,0.002448611,0.00004857903,0.0009305208,0.002360095,0.000044757,0.0001540273,0.004388633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09333666,"threshold_uncertainty_score":0.9999425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2086152618099291,"score_gpt":0.3951926477424931,"score_spread":0.1865773859325639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}