{"id":"W2058693828","doi":"10.1210/en.2013-1916","title":"Implantation Failure in Female Kiss1−/− Mice Is Independent of Their Hypogonadic State and Can Be Partially Rescued by Leukemia Inhibitory Factor","year":2014,"lang":"en","type":"article","venue":"Endocrinology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Children’s Health Research Institute; Lawson Health Research Institute","funders":"Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Queen's University; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Children's Health Research Institute; Charles A. King Trust","keywords":"Kisspeptin; Leukemia inhibitory factor; Internal medicine; Endocrinology; Uterus; Biology; Decidualization; Embryo; Hypogonadotropic hypogonadism; Leukemia inhibitory factor receptor; Hormone; Cytokine; Medicine; Cell biology; Interleukin 6","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023515,0.00128035,0.0006034008,0.001276918,0.0004191014,0.0005117767,0.0006757801,0.0007832133,0.005035196],"category_scores_gemma":[0.0002436783,0.0005822967,0.0006647485,0.0002416552,0.0008307786,0.0003957738,0.0006548117,0.001912439,0.001653084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003088332,"about_ca_system_score_gemma":0.0004422212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005466202,"about_ca_topic_score_gemma":0.001269614,"domain_scores_codex":[0.9996539,0.00002884114,0.00005180732,0.0001076488,0.00009984503,0.00005790155],"domain_scores_gemma":[0.9993492,0.00007206069,0.0002331816,0.00007098824,0.00002228106,0.0002523741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001391135,0.00002636013,0.000255394,0.00003334099,0.000008133057,0.0001672059,0.00002629159,0.00004102893,0.998091,0.0001593871,0.00005115076,0.001001633],"study_design_scores_gemma":[0.0001140428,0.0006263342,0.01360874,0.0000512017,0.00006145037,0.002843931,0.0001203986,0.001092683,0.9745649,0.0003523742,0.006527807,0.0000361237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844735,0.002051758,0.00649539,0.0004205379,0.0001828971,0.00006847935,0.00300415,0.0008599443,0.002443426],"genre_scores_gemma":[0.9584374,0.002795071,0.007158835,0.0002789399,0.00009326918,0.000315773,0.003893391,0.0006468332,0.02638044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005035196,"threshold_uncertainty_score":0.01684439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01389141616454136,"score_gpt":0.2450016870169768,"score_spread":0.2311102708524354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}