{"id":"W2058726041","doi":"10.1158/1538-7445.pedcan-b20","title":"Abstract B20: Innate and adaptive immune control of neoantigen-bearing acute lymphoblastic leukemia (ALL) enhanced by epitope spread","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Leukemia; Biology; Immunology; Adoptive cell transfer; Immune system; Epitope; Bone marrow; Cancer research; Antigen; Molecular biology; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001611355,0.0003603225,0.0001662577,0.0002183262,0.0001127679,0.0002780933,0.0001683019,0.0002241307,0.001590768],"category_scores_gemma":[0.00007212664,0.0001106065,0.0001513278,0.0001009818,0.00022218,0.0001506129,0.0002091761,0.0005221618,0.0005960796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002938731,"about_ca_system_score_gemma":0.000123059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000329951,"about_ca_topic_score_gemma":0.0003202369,"domain_scores_codex":[0.9998727,0.00002209167,0.000008400364,0.00002779773,0.00002762363,0.00004136583],"domain_scores_gemma":[0.9999305,0.000005744036,0.00001831521,0.000006040937,0.000005954011,0.00003340641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007913655,0.00002183471,0.00006931582,0.00001202972,7.617494e-7,0.00002012776,0.000005217083,0.00002854521,0.9991061,0.00006375225,0.00002087373,0.0005723384],"study_design_scores_gemma":[0.00009224036,0.001251878,0.006909338,0.00001270682,0.00001450057,0.0004652397,0.00004890344,0.001667987,0.9851213,0.0001656128,0.004243692,0.000006699934],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9957136,0.000842319,0.00168715,0.00006947044,0.0000192559,0.00003497904,0.0001972797,0.0001091366,0.0013268],"genre_scores_gemma":[0.9963521,0.0004237265,0.001035252,0.00005754938,0.00001083231,0.00003131819,0.00024673,0.0000277166,0.00181493],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001590768,"threshold_uncertainty_score":0.005321622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02218715135711857,"score_gpt":0.3367076261530409,"score_spread":0.3145204747959223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}