{"id":"W2058769093","doi":"10.1111/j.1538-7836.2009.03311.x","title":"Functional analysis of mutant variants of thrombin-activatable fibrinolysis inhibitor resistant to activation by thrombin or plasmin","year":2009,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Windsor; Queen's University","funders":"","keywords":"Thrombin; Plasmin; Thrombomodulin; Fibrinolysis; Chemistry; Zymogen; Biochemistry; Protease; Mutant; Cleavage (geology); Protein C; Scissile bond; Enzyme; Biology; Platelet; Gene; Immunology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004088335,0.001130086,0.0005845234,0.0004738503,0.0003702256,0.0007747281,0.001096346,0.0008885878,0.003336139],"category_scores_gemma":[0.0007107249,0.000348766,0.0008812682,0.0004079156,0.0008181974,0.0002626299,0.0004103747,0.001451931,0.001349511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005595146,"about_ca_system_score_gemma":0.0003201646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002299513,"about_ca_topic_score_gemma":0.00110733,"domain_scores_codex":[0.9994994,0.0001490639,0.00007957828,0.00007472245,0.0001193675,0.00007783098],"domain_scores_gemma":[0.9992527,0.0002784506,0.0002061108,0.00007633769,0.00006813816,0.000118182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003939267,0.0001062598,0.0001496189,0.00003131311,0.00004059849,0.0002899558,0.00004068015,0.0002765079,0.9974612,0.000452492,0.00007556255,0.0006819358],"study_design_scores_gemma":[0.0001860789,0.0005404645,0.00309689,0.00001660296,0.0001260931,0.002501868,0.0001062916,0.005289799,0.9841138,0.0001368102,0.003832411,0.0000528229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907845,0.0005749374,0.005791007,0.0002067488,0.0001781758,0.00007389474,0.001213918,0.0001033723,0.001073347],"genre_scores_gemma":[0.9931677,0.0002344754,0.002424523,0.00007564906,0.00003236984,0.0000465951,0.00122622,0.0001723791,0.002620155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003336139,"threshold_uncertainty_score":0.01116049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0604419796732471,"score_gpt":0.316791453241224,"score_spread":0.2563494735679769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}