{"id":"W2058824016","doi":"10.1523/jneurosci.0898-11.2011","title":"Pitx3 Is a Critical Mediator of GDNF-Induced BDNF Expression in Nigrostriatal Dopaminergic Neurons","year":2011,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Impact","funders":"National Key Research and Development Program of China; Bundesministerium für Bildung und Forschung; National Natural Science Foundation of China; European Commission","keywords":"Glial cell line-derived neurotrophic factor; Substantia nigra; Pars compacta; Neurotrophic factors; Neuroscience; Transcription factor; GDNF family of ligands; Dopaminergic; Mediator; Dopamine; Biology; Cell biology; Internal medicine; Medicine; Receptor; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004941511,0.0001667847,0.0003434688,0.0003887103,0.0001044263,0.00004789075,0.0008224649,0.00006971005,0.0001256319],"category_scores_gemma":[0.003557601,0.0001314063,0.0001490144,0.0007680375,0.0003230798,0.0007233659,0.0001586505,0.0004877997,0.000008557575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000237416,"about_ca_system_score_gemma":0.0001427296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008318485,"about_ca_topic_score_gemma":9.403163e-7,"domain_scores_codex":[0.9973998,0.0002381236,0.0007708285,0.0003637889,0.0008380379,0.0003893909],"domain_scores_gemma":[0.9986145,0.0003501257,0.0004344048,0.0002439638,0.00009374076,0.0002632558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007123352,0.00026588,0.001399242,0.00001099886,2.21128e-7,0.0002222755,0.0006198495,0.000004964726,0.9967949,0.0002316218,0.0001348126,0.0002440226],"study_design_scores_gemma":[0.0004782368,0.0008589691,0.01129513,0.00009679928,0.000006468851,0.0002845952,0.0001227534,0.0003935863,0.9857956,0.0001994898,0.0003327734,0.0001356202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977224,0.0000272592,0.0001315916,0.0002680697,0.001312812,0.00008087293,0.000007553058,0.00001114483,0.0004382376],"genre_scores_gemma":[0.998794,0.00005869796,0.0003549225,0.0006487797,0.00009367715,0.000001070274,2.978812e-8,0.00001899537,0.0000298408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0109993,"threshold_uncertainty_score":0.5358593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09288703952380606,"score_gpt":0.3042817304826527,"score_spread":0.2113946909588466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}