{"id":"W2058889082","doi":"10.1210/en.2011-1954","title":"Disruption of the Murine Glp2r Impairs Paneth Cell Function and Increases Susceptibility to Small Bowel Enteritis","year":2012,"lang":"en","type":"article","venue":"Endocrinology","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; University of Toronto; Synchrotron Light Research Institute; University Health Network","keywords":"Paneth cell; Glucagon-like peptide-2; Crypt; Internal medicine; Biology; Enteroendocrine cell; Barrier function; Endocrinology; Intestinal mucosa; Ileitis; Keratinocyte growth factor; Enterocyte; Ileum; Small intestine; Immunology; Receptor; Medicine; Growth factor; Cell biology; Endocrine system; Crohn's disease; Peptide; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417296,0.0007669196,0.000393272,0.0008046554,0.0001577252,0.0004112196,0.0003382013,0.0007220518,0.002199514],"category_scores_gemma":[0.0002216578,0.0004946987,0.000462169,0.0002148255,0.0004517236,0.0004026944,0.0003537295,0.0008997726,0.0006626782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000339775,"about_ca_system_score_gemma":0.0001592963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003576709,"about_ca_topic_score_gemma":0.0005433396,"domain_scores_codex":[0.9996324,0.00008166466,0.00005502276,0.00008026879,0.00006950608,0.00008112703],"domain_scores_gemma":[0.999482,0.00005683937,0.0002101332,0.00004838943,0.00001524796,0.0001874346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003915081,0.00009760912,0.0004018238,0.00002112661,0.000008738146,0.0001047867,0.00001824858,0.00008731986,0.9982729,0.00004651022,0.00002198757,0.0005274595],"study_design_scores_gemma":[0.0002202746,0.005067673,0.03988852,0.00004065174,0.0000863907,0.002741847,0.000179845,0.002342563,0.9471042,0.000166266,0.002128846,0.00003294836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980798,0.0004390717,0.000657042,0.00004318329,0.00001328578,0.00002245845,0.0002235188,0.0001012299,0.0004204002],"genre_scores_gemma":[0.994753,0.0005854744,0.001421385,0.00006950535,0.00001269488,0.00006697512,0.0004328714,0.00007322602,0.00258475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002199514,"threshold_uncertainty_score":0.007358074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01671969475549889,"score_gpt":0.2499497310811836,"score_spread":0.2332300363256847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}