{"id":"W2058897395","doi":"10.1016/j.jphs.2015.04.002","title":"Effect of enhanced expression of connexin 43 on sunitinib-induced cytotoxicity in mesothelioma cells","year":2015,"lang":"en","type":"article","venue":"Journal of Pharmacological Sciences","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Chiba University; University of British Columbia; Takeda Science Foundation","keywords":"Connexin; Apoptosis; Sunitinib; Cytotoxicity; Chemistry; Cell culture; Cell biology; Cancer research; Tyrosine kinase; Gap junction; Intracellular; Molecular biology; Signal transduction; Biology; In vitro; Cancer; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002098205,0.0001054289,0.0003082701,0.0001072626,0.00002586547,0.000004967158,0.0003392614,0.0001218965,0.00007456636],"category_scores_gemma":[0.0003664228,0.00006038408,0.0001053835,0.0001891163,0.0002645572,0.000006588058,0.0000762753,0.0001336654,0.000001357843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001337904,"about_ca_system_score_gemma":0.00009852645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007623039,"about_ca_topic_score_gemma":0.000003231165,"domain_scores_codex":[0.998509,0.0005218722,0.0004108291,0.0001600501,0.000223171,0.0001750804],"domain_scores_gemma":[0.9990786,0.000207398,0.0004194904,0.00006255992,0.00012562,0.0001063336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001159895,0.0001644106,0.0006507548,0.000007092093,0.00001051121,0.000008887094,0.0000388367,0.000145578,0.9963067,0.00001331884,0.0001466269,0.001347404],"study_design_scores_gemma":[0.00145801,0.01195249,0.0005454656,0.00003086472,0.00001304092,0.000008834955,0.00008769993,0.00002516396,0.9855876,0.00004387522,0.0001780105,0.00006896146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985695,0.0001462869,0.00003774142,0.0000789917,0.0001979563,0.0001154959,0.000005250469,0.000001428418,0.0008473577],"genre_scores_gemma":[0.9995884,0.00006687905,0.0001157251,0.000106183,0.0001069591,0.000002311711,5.933245e-7,0.000002527877,0.00001041339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01178808,"threshold_uncertainty_score":0.2462391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04441173970325136,"score_gpt":0.365794388684166,"score_spread":0.3213826489809146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}