{"id":"W2058901492","doi":"10.1039/b9pp00109c","title":"Structure-activity relationships of mono-substituted trisulfonated porphyrazines for the photodynamic therapy (PDT) of cancer","year":2010,"lang":"en","type":"article","venue":"Photochemical & Photobiological Sciences","topic":"Porphyrin and Phthalocyanine Chemistry","field":"Materials Science","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"","keywords":"Porphyrazine; Phototoxicity; Lipophilicity; Chemistry; Photodynamic therapy; Intracellular; Side chain; Organelle; Phthalocyanine; Biophysics; Stereochemistry; In vitro; Biochemistry; Photochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002099313,0.0001837492,0.0001317786,0.0001745059,0.00007705516,0.0001709781,0.0001938744,0.0002043081,0.0009752375],"category_scores_gemma":[0.0002065942,0.000128617,0.0001428658,0.000170715,0.0001081874,0.0001630475,0.0000818027,0.0002254088,0.0001400441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002407294,"about_ca_system_score_gemma":0.0001857133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007496329,"about_ca_topic_score_gemma":0.0012697,"domain_scores_codex":[0.9999408,0.00001521946,0.000004843157,0.00000792484,0.00001536248,0.00001580898],"domain_scores_gemma":[0.9999214,0.00002520604,0.00002109704,0.000005201902,0.00001116952,0.00001588058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007476217,0.00009352414,0.0002846739,0.00005478947,0.000009394637,0.00003644921,0.00002233876,0.0009259791,0.9928724,0.0001590588,0.00005580891,0.004738011],"study_design_scores_gemma":[0.00004928939,0.001919892,0.001786475,0.000004152996,0.00002511073,0.0001205097,0.000009401027,0.002377922,0.9929006,0.00003062588,0.000770746,0.000005406149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969128,0.001962058,0.0004216637,0.00002903027,0.000005727865,0.00001020337,0.00007239046,0.00001604068,0.0005700691],"genre_scores_gemma":[0.9977488,0.0009948958,0.0004316298,0.00001113584,0.000002486182,0.00000563517,0.0001214276,0.000002919016,0.0006810111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009752375,"threshold_uncertainty_score":0.00326252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05247141195318838,"score_gpt":0.3281623193724134,"score_spread":0.275690907419225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}