{"id":"W2058947545","doi":"10.1007/s10549-007-9711-8","title":"Anti-estrogenic mechanism of unliganded progesterone receptor isoform B in breast cancer cells","year":2007,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; University of Illinois at Urbana-Champaign","keywords":"Progesterone receptor; Breast cancer; Internal medicine; Endocrinology; Gene isoform; Mechanism (biology); Oestrogen receptor; Estrogen receptor; Receptor; Cancer; Medicine; Biology; Cancer research; Physics; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001384097,0.0001699095,0.0001713597,0.0001826396,0.0002191627,0.0003053379,0.0002547585,0.0002123714,0.002465154],"category_scores_gemma":[0.0001370472,0.0001280354,0.0002071929,0.0001509587,0.0001606506,0.0002335753,0.0001202721,0.0003530161,0.0005065157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003058932,"about_ca_system_score_gemma":0.0002159356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001241978,"about_ca_topic_score_gemma":0.0008938242,"domain_scores_codex":[0.9999193,0.00001920938,0.000004531665,0.00001136181,0.00001784853,0.00002770353],"domain_scores_gemma":[0.9999404,0.00001342403,0.000007552592,0.0000143609,0.00001095407,0.00001337378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005882405,0.00007796659,0.0004085274,0.00007286885,0.00001011279,0.0001458173,0.00003932621,0.00005854003,0.9926026,0.0008462577,0.0002555705,0.004894173],"study_design_scores_gemma":[0.0001351105,0.000757614,0.01631,0.00001455828,0.00003342766,0.0009675928,0.0001832269,0.0007767138,0.9636136,0.0002784271,0.01692295,0.000006861876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841999,0.00965739,0.001104764,0.0004903401,0.0001206725,0.00002085396,0.000370338,0.00006549434,0.003970134],"genre_scores_gemma":[0.9919286,0.002878111,0.0003194142,0.00011248,0.00002626154,0.00001885723,0.0004034945,0.000008244619,0.004304498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002465154,"threshold_uncertainty_score":0.008246779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01651958473676404,"score_gpt":0.3187768292523359,"score_spread":0.3022572445155718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}