{"id":"W2058963225","doi":"10.1038/sj.gt.3302797","title":"HER-2/neu-gene engineered dendritic cell vaccine stimulates stronger HER-2/neu-specific immune responses compared to DNA vaccination","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Cancer Agency","keywords":"DNA vaccination; Biology; HER2/neu; Immune system; Dendritic cell; Vaccination; Immunology; Antigen; Genetic enhancement; Naked DNA; Cancer research; Transgene; Cancer; Breast cancer; Gene; Immunization; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003735747,0.0006407199,0.0008225486,0.0004326908,0.0001685717,0.000517599,0.0002246932,0.0005745821,0.002178358],"category_scores_gemma":[0.000356834,0.0002106106,0.0003459791,0.0002552631,0.0003297029,0.0004551996,0.000372215,0.001392945,0.0005227042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000408141,"about_ca_system_score_gemma":0.0004009983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003272054,"about_ca_topic_score_gemma":0.0005267961,"domain_scores_codex":[0.9995683,0.00008321921,0.00002575008,0.00008114938,0.00008501609,0.0001566826],"domain_scores_gemma":[0.9997277,0.0001135544,0.00003830701,0.00003241192,0.00003146256,0.00005657631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004966963,0.000224147,0.0001036226,0.00005954026,0.00001144178,0.00003240502,0.00001680223,0.0001723044,0.9962319,0.0001347029,0.00006971372,0.00244684],"study_design_scores_gemma":[0.0001283307,0.001213767,0.001013532,0.000008371583,0.00003952087,0.0001675363,0.00002516576,0.001059409,0.9950444,0.0001132252,0.001181137,0.000005614758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936062,0.0008680079,0.002940865,0.0001278685,0.0002060732,0.0000722546,0.0001312273,0.00008803802,0.001959443],"genre_scores_gemma":[0.9956495,0.00039337,0.001809779,0.0001377,0.00005934751,0.00004332357,0.000141018,0.00002904643,0.001736952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002178358,"threshold_uncertainty_score":0.007287383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01366044133277848,"score_gpt":0.236089697317357,"score_spread":0.2224292559845785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}