{"id":"W2058963225","doi":"10.1038/sj.gt.3302797","title":"HER-2/neu-gene engineered dendritic cell vaccine stimulates stronger HER-2/neu-specific immune responses compared to DNA vaccination","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Cancer Agency","keywords":"DNA vaccination; Biology; HER2/neu; Immune system; Dendritic cell; Vaccination; Immunology; Antigen; Genetic enhancement; Naked DNA; Cancer research; Transgene; Cancer; Breast cancer; Gene; Immunization; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005829661,0.0007218875,0.0008830232,0.0005714759,0.0005241195,0.0001266977,0.0007353074,0.0004292191,0.002761954],"category_scores_gemma":[0.00002906327,0.000685414,0.0003274298,0.0005948608,0.00007045854,0.0002727447,0.00009576083,0.0004390932,0.001140595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001821616,"about_ca_system_score_gemma":0.000128022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002643658,"about_ca_topic_score_gemma":0.00002283946,"domain_scores_codex":[0.996157,0.0008162748,0.001022297,0.000771851,0.0001494017,0.001083173],"domain_scores_gemma":[0.9978156,0.0005034471,0.0002451299,0.001120239,0.0002555499,0.00006002145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009718675,0.0006937552,0.0004037702,0.00001234941,0.0002700143,0.00001824129,0.0004713564,0.001175751,0.9762511,0.00005298705,0.002628704,0.008303356],"study_design_scores_gemma":[0.007213067,0.0008274967,0.08463233,0.00002858069,0.00003026164,0.00007816356,0.0001551732,0.00001539941,0.8468755,0.00007834999,0.05938708,0.0006785254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9023917,0.09325018,0.000926514,0.0005409005,0.00130327,0.0009890101,0.00009907207,0.0003349794,0.0001643745],"genre_scores_gemma":[0.9854521,0.002590804,0.0006442172,0.0003014781,0.0001979415,0.0001378687,0.0005650172,0.0001481983,0.009962396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1293755,"threshold_uncertainty_score":0.9996371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01366044133277848,"score_gpt":0.236089697317357,"score_spread":0.2224292559845785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}