{"id":"W2058968882","doi":"10.1371/journal.pone.0021602","title":"TSPYL2 Is Important for G1 Checkpoint Maintenance upon DNA Damage","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Hong Kong; University of Toronto","keywords":"Cell biology; DNA damage; G2-M DNA damage checkpoint; Biology; Cell cycle checkpoint; Chromatin; Cell cycle; Chromatin remodeling; DNA repair; Mutant; CHEK1; Transcription factor; Molecular biology; Apoptosis; DNA; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005943403,0.0003975544,0.0001885336,0.0002125535,0.0002706241,0.0002624587,0.0001710081,0.0002853688,0.001366112],"category_scores_gemma":[0.00007800355,0.0001436062,0.0002246365,0.0001438508,0.0001627547,0.0001541713,0.0002584784,0.0002548958,0.000510653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002797108,"about_ca_system_score_gemma":0.0001812615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006445365,"about_ca_topic_score_gemma":0.001013348,"domain_scores_codex":[0.9999329,0.000006819504,0.000004658657,0.00002291349,0.00001741345,0.0000153824],"domain_scores_gemma":[0.9999131,0.000006681274,0.00003252849,0.000007126587,0.000009495291,0.00003104852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007292272,0.000003794225,0.0003388138,0.00002027242,0.000003105735,0.0001785101,0.000007628556,0.00003257451,0.9987158,0.00005455392,0.00004113601,0.0005309905],"study_design_scores_gemma":[0.00001951075,0.0001546398,0.0265917,0.000007916602,0.00002388041,0.002533248,0.00004043018,0.0009049947,0.961601,0.0001209287,0.007993366,0.00000848407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905804,0.002826815,0.004029385,0.0001100787,0.00002860963,0.00001348799,0.0009542324,0.0001505889,0.001306556],"genre_scores_gemma":[0.9911528,0.0008352374,0.002045311,0.00004334595,0.00001543467,0.00001646696,0.002007477,0.00004691018,0.003836909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001366112,"threshold_uncertainty_score":0.004570067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03995614173117416,"score_gpt":0.2271844837648,"score_spread":0.1872283420336258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}